rs10273199

Homo sapiens
A>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0059 (1788/29958,GnomAD)
C=0055 (1606/29118,TOPMED)
C=0046 (228/5008,1000G)
C=0092 (355/3854,ALSPAC)
C=0089 (330/3708,TWINSUK)
chr7:50167951 (GRCh38.p7) (7p12.2)
AD
GWASdb2
1   publication(s)
See rs on genome
6 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.50167951A>C
GRCh37.p13 chr 7NC_000007.13:g.50207547A>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.996C=0.004
1000GenomesAmericanSub694A=0.950C=0.050
1000GenomesEast AsianSub1008A=0.970C=0.030
1000GenomesEuropeSub1006A=0.914C=0.086
1000GenomesGlobalStudy-wide5008A=0.954C=0.046
1000GenomesSouth AsianSub978A=0.930C=0.070
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.908C=0.092
The Genome Aggregation DatabaseAfricanSub8726A=0.983C=0.017
The Genome Aggregation DatabaseAmericanSub838A=0.940C=0.060
The Genome Aggregation DatabaseEast AsianSub1622A=0.978C=0.022
The Genome Aggregation DatabaseEuropeSub18470A=0.917C=0.082
The Genome Aggregation DatabaseGlobalStudy-wide29958A=0.940C=0.059
The Genome Aggregation DatabaseOtherSub302A=0.910C=0.090
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.944C=0.055
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.911C=0.089
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs102731990.000178alcohol dependence21314694

eQTL of rs10273199 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10273199 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr75024478550245460E07137238
chr75024692950247025E07139382
chr75025604950256191E07148502
chr75025624250256313E07148695
chr75025632150256443E07148774
chr75025648250256536E07148935