rs1028575

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0269 (8077/29936,GnomAD)
T==0257 (7501/29118,TOPMED)
T==0274 (1374/5008,1000G)
T==0204 (785/3854,ALSPAC)
T==0203 (751/3708,TWINSUK)
chr1:86501168 (GRCh38.p7) (1p22.3)
ND
GWASdb2
1   publication(s)
See rs on genome
26 Enhancers around
2 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 1NC_000001.11:g.86501168T>C
GRCh37.p13 chr 1NC_000001.10:g.86966851T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.336C=0.664
1000GenomesAmericanSub694T=0.320C=0.680
1000GenomesEast AsianSub1008T=0.298C=0.702
1000GenomesEuropeSub1006T=0.216C=0.784
1000GenomesGlobalStudy-wide5008T=0.274C=0.726
1000GenomesSouth AsianSub978T=0.190C=0.810
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.204C=0.796
The Genome Aggregation DatabaseAfricanSub8700T=0.325C=0.675
The Genome Aggregation DatabaseAmericanSub836T=0.260C=0.740
The Genome Aggregation DatabaseEast AsianSub1616T=0.293C=0.707
The Genome Aggregation DatabaseEuropeSub18482T=0.242C=0.757
The Genome Aggregation DatabaseGlobalStudy-wide29936T=0.269C=0.730
The Genome Aggregation DatabaseOtherSub302T=0.280C=0.720
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.257C=0.742
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.203C=0.797
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs10285750.000234nicotine dependence17158188

eQTL of rs1028575 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1028575 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr18695235786953713E067-13138
chr18696679286966896E0670
chr18697042386970632E0673572
chr18697068386971396E0673832
chr18695235786953713E068-13138
chr18697042386970632E0683572
chr18697068386971396E0683832
chr18701448087015091E06847629
chr18694109086941147E069-25704
chr18697042386970632E0693572
chr18697068386971396E0693832
chr18701448087015091E06947629
chr18697068386971396E0703832
chr18695235786953713E071-13138
chr18697005586970139E0713204
chr18697042386970632E0713572
chr18697068386971396E0713832
chr18697068386971396E0723832
chr18701448087015091E07247629
chr18694109086941147E074-25704
chr18697005586970139E0743204
chr18697042386970632E0743572
chr18697068386971396E0743832
chr18701448087015091E07447629
chr18697042386970632E0823572
chr18697068386971396E0823832








Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr18696786986968323E0681018
chr18696786986968323E0721018