rs1036517

Homo sapiens
G>A
LOC105369212 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
G==0254 (7613/29940,GnomAD)
G==0255 (7429/29118,TOPMED)
G==0291 (1459/5008,1000G)
G==0317 (1222/3854,ALSPAC)
G==0321 (1191/3708,TWINSUK)
chr15:96102971 (GRCh38.p7) (15q26.2)
AD
GWASdb2
1   publication(s)
See rs on genome
16 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 15NC_000015.10:g.96102971G>A
GRCh37.p13 chr 15NC_000015.9:g.96646200G>A

Gene: LOC105369212, uncharacterized LOC105369212(minus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC105369212 transcript variant X2XR_001751686.1:n.N/AIntron Variant
LOC105369212 transcript variant X1XR_932659.2:n.N/AGenic Downstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.120A=0.880
1000GenomesAmericanSub694G=0.300A=0.700
1000GenomesEast AsianSub1008G=0.278A=0.722
1000GenomesEuropeSub1006G=0.338A=0.662
1000GenomesGlobalStudy-wide5008G=0.291A=0.709
1000GenomesSouth AsianSub978G=0.480A=0.520
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.317A=0.683
The Genome Aggregation DatabaseAfricanSub8722G=0.150A=0.850
The Genome Aggregation DatabaseAmericanSub836G=0.300A=0.700
The Genome Aggregation DatabaseEast AsianSub1612G=0.272A=0.728
The Genome Aggregation DatabaseEuropeSub18470G=0.296A=0.703
The Genome Aggregation DatabaseGlobalStudy-wide29940G=0.254A=0.745
The Genome Aggregation DatabaseOtherSub300G=0.460A=0.540
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.255A=0.744
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.321A=0.679
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs10365178.1E-05alcohol dependence24277619

eQTL of rs1036517 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1036517 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr159663035296631219E070-14981
chr159663123896631385E070-14815
chr159663148996631591E070-14609
chr159663181496631889E070-14311
chr159663191296632143E070-14057
chr159663216396632358E070-13842
chr159663242696632568E070-13632
chr159663260696632712E070-13488
chr159663287896633160E070-13040
chr159659779496597860E081-48340
chr159661348796613766E081-32434
chr159661385896614241E081-31959
chr159661426296614346E081-31854
chr159661440896614595E081-31605
chr159661471096614760E081-31440
chr159663123896631385E081-14815