rs1036536

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0287 (8602/29922,GnomAD)
C==0317 (9253/29118,TOPMED)
C==0345 (1727/5008,1000G)
C==0222 (857/3854,ALSPAC)
C==0240 (889/3708,TWINSUK)
chr12:70117766 (GRCh38.p7) (12q15)
AD
GWASdb2
1   publication(s)
See rs on genome
2 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 12NC_000012.12:g.70117766C>T
GRCh37.p13 chr 12NC_000012.11:g.70511546C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.390T=0.610
1000GenomesAmericanSub694C=0.250T=0.750
1000GenomesEast AsianSub1008C=0.501T=0.499
1000GenomesEuropeSub1006C=0.232T=0.768
1000GenomesGlobalStudy-wide5008C=0.345T=0.655
1000GenomesSouth AsianSub978C=0.310T=0.690
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.222T=0.778
The Genome Aggregation DatabaseAfricanSub8706C=0.369T=0.631
The Genome Aggregation DatabaseAmericanSub838C=0.230T=0.770
The Genome Aggregation DatabaseEast AsianSub1618C=0.486T=0.514
The Genome Aggregation DatabaseEuropeSub18458C=0.233T=0.766
The Genome Aggregation DatabaseGlobalStudy-wide29922C=0.287T=0.712
The Genome Aggregation DatabaseOtherSub302C=0.320T=0.680
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.317T=0.682
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.240T=0.760
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs10365360.00095alcohol dependence20201924

eQTL of rs1036536 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1036536 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr127046418970464725E071-46821
chr127046479770464912E071-46634