rs1036668

Homo sapiens
G>T
None
Check p-value
SNV (Single Nucleotide Variation)
G==0245 (7354/29916,GnomAD)
G==0248 (7222/29116,TOPMED)
G==0254 (1272/5008,1000G)
G==0239 (920/3854,ALSPAC)
G==0255 (945/3708,TWINSUK)
chr2:11992512 (GRCh38.p7) (2p25.1)
AD
GWASdb2
1   publication(s)
See rs on genome
22 Enhancers around
6 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.11992512G>T
GRCh37.p13 chr 2NC_000002.11:g.12132638G>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.281T=0.719
1000GenomesAmericanSub694G=0.280T=0.720
1000GenomesEast AsianSub1008G=0.237T=0.763
1000GenomesEuropeSub1006G=0.238T=0.762
1000GenomesGlobalStudy-wide5008G=0.254T=0.746
1000GenomesSouth AsianSub978G=0.230T=0.770
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.239T=0.761
The Genome Aggregation DatabaseAfricanSub8686G=0.259T=0.741
The Genome Aggregation DatabaseAmericanSub836G=0.310T=0.690
The Genome Aggregation DatabaseEast AsianSub1614G=0.245T=0.755
The Genome Aggregation DatabaseEuropeSub18478G=0.237T=0.762
The Genome Aggregation DatabaseGlobalStudy-wide29916G=0.245T=0.754
The Genome Aggregation DatabaseOtherSub302G=0.200T=0.800
Trans-Omics for Precision MedicineGlobalStudy-wide29116G=0.248T=0.752
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.255T=0.745
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs10366680.000971alcohol dependence24277619

eQTL of rs1036668 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1036668 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr21217198012172382E06939342
chr21209578312095952E070-36686
chr21210804812108629E070-24009
chr21210869812109028E070-23610
chr21214572912145892E07013091
chr21214593212146067E07013294
chr21214609312146465E07013455
chr21214648512146621E07013847
chr21209578312095952E081-36686
chr21210804812108629E081-24009
chr21215759912157701E08124961
chr21215771312157952E08125075
chr21215802412158106E08125386
chr21217198012172382E08139342
chr21210804812108629E082-24009
chr21214572912145892E08213091
chr21214593212146067E08213294
chr21214609312146465E08213455
chr21214648512146621E08213847
chr21215759912157701E08224961
chr21215771312157952E08225075
chr21215802412158106E08225386




Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr21209601712096528E067-36110
chr21209601712096528E070-36110
chr21209601712096528E071-36110
chr21209601712096528E072-36110
chr21209601712096528E073-36110
chr21209601712096528E074-36110