SNP Detail Info-rs1037112

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A==0407 (12150/29854,GnomAD)
A==0474 (13829/29118,TOPMED)
G=0492 (2465/5008,1000G)
A==0309 (1189/3854,ALSPAC)
A==0321 (1191/3708,TWINSUK)

Position: chr5:13373983 (GRCh38.p7) (5p15.2)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 2 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 5	NC_000005.10:g.13373983A>G
GRCh37.p13 chr 5	NC_000005.9:g.13374095A>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.654	G=0.346
1000Genomes	American	Sub	694	A=0.460	G=0.540
1000Genomes	East Asian	Sub	1008	A=0.548	G=0.452
1000Genomes	Europe	Sub	1006	A=0.321	G=0.679
1000Genomes	Global	Study-wide	5008	A=0.508	G=0.492
1000Genomes	South Asian	Sub	978	A=0.500	G=0.500
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.309	G=0.691
The Genome Aggregation Database	African	Sub	8668	A=0.625	G=0.375
The Genome Aggregation Database	American	Sub	838	A=0.460	G=0.540
The Genome Aggregation Database	East Asian	Sub	1590	A=0.486	G=0.514
The Genome Aggregation Database	Europe	Sub	18458	A=0.297	G=0.702
The Genome Aggregation Database	Global	Study-wide	29854	A=0.407	G=0.593
The Genome Aggregation Database	Other	Sub	300	A=0.240	G=0.760
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.474	G=0.525
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.321	G=0.679

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs1037112	0.00012	alcohol dependence(early age of onset)	20201924
rs1037112	0.00032	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr5	13358554	13358672	E082	-15423
chr5	13359452	13359758	E082	-14337

rs1037112