rs1038235

Homo sapiens
T>C
ADAMTS17 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0236 (7086/29906,GnomAD)
C=0252 (7341/29118,TOPMED)
C=0234 (1171/5008,1000G)
C=0170 (656/3854,ALSPAC)
C=0172 (637/3708,TWINSUK)
chr15:100195762 (GRCh38.p7) (15q26.3)
ND
GWASdb2
1   publication(s)
See rs on genome
73 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 15NC_000015.10:g.100195762T>C
GRCh37.p13 chr 15NC_000015.9:g.100735967T>C
ADAMTS17 RefSeqGeneNG_016287.1:g.151217A>G

Gene: ADAMTS17, ADAM metallopeptidase with thrombospondin type 1 motif 17(minus strand)

Molecule type Change Amino acid[Codon] SO Term
ADAMTS17 transcriptNM_139057.2:c.N/AIntron Variant
ADAMTS17 transcript variant X5XM_005254872.3:c.N/AIntron Variant
ADAMTS17 transcript variant X4XM_011521312.2:c.N/AIntron Variant
ADAMTS17 transcript variant X1XM_017021973.1:c.N/AIntron Variant
ADAMTS17 transcript variant X2XM_017021974.1:c.N/AIntron Variant
ADAMTS17 transcript variant X3XM_017021975.1:c.N/AIntron Variant
ADAMTS17 transcript variant X6XM_017021976.1:c.N/AIntron Variant
ADAMTS17 transcript variant X7XM_017021977.1:c.N/AIntron Variant
ADAMTS17 transcript variant X11XM_017021978.1:c.N/AIntron Variant
ADAMTS17 transcript variant X12XM_017021979.1:c.N/AIntron Variant
ADAMTS17 transcript variant X14XM_017021981.1:c.N/AIntron Variant
ADAMTS17 transcript variant X17XM_017021984.1:c.N/AIntron Variant
ADAMTS17 transcript variant X13XM_017021980.1:c.N/AGenic Upstream Transcript Variant
ADAMTS17 transcript variant X15XM_017021982.1:c.N/AGenic Upstream Transcript Variant
ADAMTS17 transcript variant X16XM_017021983.1:c.N/AGenic Upstream Transcript Variant
ADAMTS17 transcript variant X8XR_001751118.1:n.N/AIntron Variant
ADAMTS17 transcript variant X9XR_001751119.1:n.N/AIntron Variant
ADAMTS17 transcript variant X10XR_001751120.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.614C=0.386
1000GenomesAmericanSub694T=0.880C=0.120
1000GenomesEast AsianSub1008T=0.746C=0.254
1000GenomesEuropeSub1006T=0.806C=0.194
1000GenomesGlobalStudy-wide5008T=0.766C=0.234
1000GenomesSouth AsianSub978T=0.870C=0.130
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.830C=0.170
The Genome Aggregation DatabaseAfricanSub8692T=0.649C=0.351
The Genome Aggregation DatabaseAmericanSub836T=0.880C=0.120
The Genome Aggregation DatabaseEast AsianSub1614T=0.721C=0.279
The Genome Aggregation DatabaseEuropeSub18462T=0.815C=0.184
The Genome Aggregation DatabaseGlobalStudy-wide29906T=0.763C=0.236
The Genome Aggregation DatabaseOtherSub302T=0.750C=0.250
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.747C=0.252
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.828C=0.172
PMID Title Author Journal
19268276Genome-wide association study of smoking initiation and current smoking.Vink JMAm J Hum Genet

P-Value

SNP ID p-value Traits Study
rs10382350.000501nicotine smoking19268276

eQTL of rs1038235 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1038235 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr15100764543100764689E06728576
chr15100764732100765367E06728765
chr15100692759100692979E068-42988
chr15100707746100707841E068-28126
chr15100707911100707955E068-28012
chr15100710499100710625E068-25342
chr15100710716100710838E068-25129
chr15100710960100711114E068-24853
chr15100762436100762606E06826469
chr15100762870100762948E06826903
chr15100763006100763120E06827039
chr15100764732100765367E06828765
chr15100784989100785433E06849022
chr15100785570100785662E06849603
chr15100785750100785799E06849783
chr15100785800100785886E06849833
chr15100708421100708610E069-27357
chr15100708832100708882E069-27085
chr15100764543100764689E06928576
chr15100764732100765367E06928765
chr15100701281100701435E070-34532
chr15100701735100701789E070-34178
chr15100708421100708610E070-27357
chr15100734730100734884E070-1083
chr15100735049100735127E070-840
chr15100735179100735495E070-472
chr15100736889100737028E070922
chr15100737109100737165E0701142
chr15100737394100737451E0701427
chr15100771115100771254E07035148
chr15100771526100771570E07035559
chr15100771586100771648E07035619
chr15100762870100762948E07126903
chr15100763006100763120E07127039
chr15100764543100764689E07128576
chr15100764732100765367E07128765
chr15100781812100782162E07145845
chr15100784989100785433E07149022
chr15100785570100785662E07149603
chr15100785750100785799E07149783
chr15100785800100785886E07149833
chr15100762436100762606E07226469
chr15100762870100762948E07226903
chr15100763006100763120E07227039
chr15100764732100765367E07228765
chr15100764543100764689E07328576
chr15100764732100765367E07328765
chr15100782229100782737E07346262
chr15100782793100782865E07346826
chr15100784848100784909E07348881
chr15100784989100785433E07349022
chr15100785570100785662E07349603
chr15100785750100785799E07349783
chr15100785800100785886E07349833
chr15100764732100765367E07428765
chr15100692487100692537E081-43430
chr15100692759100692979E081-42988
chr15100693419100693607E081-42360
chr15100693684100693817E081-42150
chr15100693822100694050E081-41917
chr15100735049100735127E081-840
chr15100736889100737028E081922
chr15100737109100737165E0811142
chr15100737394100737451E0811427
chr15100752237100752981E08116270
chr15100758418100758692E08122451
chr15100758743100758931E08122776
chr15100759168100759320E08123201
chr15100759365100759450E08123398
chr15100726682100726726E082-9241
chr15100726862100726912E082-9055
chr15100758418100758692E08222451
chr15100758743100758931E08222776