rs10401125

Homo sapiens
C>A / C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0279 (8369/29906,GnomAD)
T=0251 (7320/29118,TOPMED)
T=0269 (1345/5008,1000G)
T=0289 (1114/3854,ALSPAC)
T=0293 (1087/3708,TWINSUK)
chr18:78576288 (GRCh38.p7) (18q23)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
1 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 18NC_000018.10:g.78576288C>A
GRCh38.p7 chr 18NC_000018.10:g.78576288C>T
GRCh37.p13 chr 18NC_000018.9:g.76336288C>A
GRCh37.p13 chr 18NC_000018.9:g.76336288C>T
GRCh38.p7 chr 18 alt locus HSCHR18_ALT21_CTG2_1NT_187665.1:g.82822C>A
GRCh38.p7 chr 18 alt locus HSCHR18_ALT21_CTG2_1NT_187665.1:g.82822C>T
GRCh38.p7 chr 18 alt locus HSCHR18_1_CTG2_1NW_003315958.1:g.82822C>A
GRCh38.p7 chr 18 alt locus HSCHR18_1_CTG2_1NW_003315958.1:g.82822C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.774T=0.226
1000GenomesAmericanSub694C=0.660T=0.340
1000GenomesEast AsianSub1008C=0.776T=0.224
1000GenomesEuropeSub1006C=0.714T=0.286
1000GenomesGlobalStudy-wide5008C=0.731T=0.269
1000GenomesSouth AsianSub978C=0.700T=0.300
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.711T=0.289
The Genome Aggregation DatabaseAfricanSub8708C=0.779T=0.221
The Genome Aggregation DatabaseAmericanSub838C=0.720T=0.28,
The Genome Aggregation DatabaseEast AsianSub1620C=0.790T=0.210
The Genome Aggregation DatabaseEuropeSub18438C=0.684T=0.315
The Genome Aggregation DatabaseGlobalStudy-wide29906C=0.720T=0.279
The Genome Aggregation DatabaseOtherSub302C=0.790T=0.21,
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.748T=0.251
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.707T=0.293
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs104011250.000367alcohol dependence20201924

eQTL of rs10401125 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10401125 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr181539039015390692E06936980