rs10410306

Homo sapiens
T>C
ZNF224 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T==0242 (7250/29938,GnomAD)
T==0288 (8399/29118,TOPMED)
T==0350 (1754/5008,1000G)
T==0123 (473/3854,ALSPAC)
T==0123 (455/3708,TWINSUK)
chr19:44097384 (GRCh38.p7) (19q13.31)
AD
GWASdb2
1   publication(s)
See rs on genome
13 Enhancers around
91 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 19NC_000019.10:g.44097384T>C
GRCh37.p13 chr 19NC_000019.9:g.44601537T>C

Gene: ZNF224, zinc finger protein 224(plus strand)

Molecule type Change Amino acid[Codon] SO Term
ZNF224 transcriptNM_001321645.1:c.N/AIntron Variant
ZNF224 transcriptNM_013398.3:c.N/AIntron Variant
ZNF224 transcript variant X1XM_017027261.1:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.455C=0.545
1000GenomesAmericanSub694T=0.450C=0.550
1000GenomesEast AsianSub1008T=0.474C=0.526
1000GenomesEuropeSub1006T=0.142C=0.858
1000GenomesGlobalStudy-wide5008T=0.350C=0.650
1000GenomesSouth AsianSub978T=0.230C=0.770
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.123C=0.877
The Genome Aggregation DatabaseAfricanSub8696T=0.387C=0.613
The Genome Aggregation DatabaseAmericanSub836T=0.460C=0.540
The Genome Aggregation DatabaseEast AsianSub1620T=0.452C=0.548
The Genome Aggregation DatabaseEuropeSub18484T=0.146C=0.853
The Genome Aggregation DatabaseGlobalStudy-wide29938T=0.242C=0.757
The Genome Aggregation DatabaseOtherSub302T=0.200C=0.800
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.288C=0.711
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.123C=0.877
PMID Title Author Journal
23743675A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.Kapoor MHum Genet

P-Value

SNP ID p-value Traits Study
rs104103068.57E-05alcohol consumption23743675

eQTL of rs10410306 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10410306 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr194455748644557536E067-44001
chr194455748644557536E068-44001
chr194461888344619034E06817346
chr194460014844600194E069-1343
chr194455793344557994E070-43543
chr194460014844600194E070-1343
chr194461888344619034E07017346
chr194461903744619091E07017500
chr194461912544619165E07017588
chr194461888344619034E07117346
chr194455748644557536E081-44001
chr194455748644557536E082-44001
chr194460081644600930E082-607







Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr194455479344554904E067-46633
chr194455494844556685E067-44852
chr194455673144556943E067-44594
chr194457541944575610E067-25927
chr194457564244577153E067-24384
chr194459804744599722E067-1815
chr194461592544616789E06714388
chr194461680644618482E06715269
chr194464488144646741E06743344
chr194455494844556685E068-44852
chr194455673144556943E068-44594
chr194457541944575610E068-25927
chr194457564244577153E068-24384
chr194459781244597885E068-3652
chr194459793544597989E068-3548
chr194459804744599722E068-1815
chr194461578744615827E06814250
chr194461592544616789E06814388
chr194461680644618482E06815269
chr194464474344644803E06843206
chr194464488144646741E06843344
chr194455494844556685E069-44852
chr194455673144556943E069-44594
chr194457541944575610E069-25927
chr194457564244577153E069-24384
chr194459804744599722E069-1815
chr194461578744615827E06914250
chr194461592544616789E06914388
chr194461680644618482E06915269
chr194464488144646741E06943344
chr194455494844556685E070-44852
chr194455673144556943E070-44594
chr194457541944575610E070-25927
chr194457564244577153E070-24384
chr194459804744599722E070-1815
chr194461592544616789E07014388
chr194461680644618482E07015269
chr194464474344644803E07043206
chr194464488144646741E07043344
chr194455494844556685E071-44852
chr194455673144556943E071-44594
chr194457541944575610E071-25927
chr194457564244577153E071-24384
chr194459804744599722E071-1815
chr194461578744615827E07114250
chr194461592544616789E07114388
chr194461680644618482E07115269
chr194464474344644803E07143206
chr194464488144646741E07143344
chr194455494844556685E072-44852
chr194455673144556943E072-44594
chr194457541944575610E072-25927
chr194457564244577153E072-24384
chr194459804744599722E072-1815
chr194461592544616789E07214388
chr194461680644618482E07215269
chr194464474344644803E07243206
chr194464488144646741E07243344
chr194455494844556685E073-44852
chr194455673144556943E073-44594
chr194457541944575610E073-25927
chr194457564244577153E073-24384
chr194459804744599722E073-1815
chr194461592544616789E07314388
chr194461680644618482E07315269
chr194464488144646741E07343344
chr194455494844556685E074-44852
chr194455673144556943E074-44594
chr194457541944575610E074-25927
chr194457564244577153E074-24384
chr194459804744599722E074-1815
chr194461592544616789E07414388
chr194461680644618482E07415269
chr194464488144646741E07443344
chr194455494844556685E081-44852
chr194455673144556943E081-44594
chr194457541944575610E081-25927
chr194457564244577153E081-24384
chr194459804744599722E081-1815
chr194461592544616789E08114388
chr194461680644618482E08115269
chr194464488144646741E08143344
chr194455494844556685E082-44852
chr194455673144556943E082-44594
chr194457541944575610E082-25927
chr194457564244577153E082-24384
chr194459804744599722E082-1815
chr194461592544616789E08214388
chr194461680644618482E08215269
chr194464474344644803E08243206
chr194464488144646741E08243344