SNP Detail Info-rs10417874

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0448 (13421/29914,GnomAD)
G==0465 (13561/29118,TOPMED)
G==0460 (2303/5008,1000G)
A=0273 (1052/3854,ALSPAC)
A=0268 (995/3708,TWINSUK)

Position: chr19:55121025 (GRCh38.p7) (19q13.42)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 27 Enhancers around

Promoter: 23 Promoters around

Sequence Name	Change(s)
GRCh38.p7 chr 19	NC_000019.10:g.55121025G>A
GRCh37.p13 chr 19	NC_000019.9:g.55632393G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.115	A=0.885
1000Genomes	American	Sub	694	G=0.630	A=0.370
1000Genomes	East Asian	Sub	1008	G=0.351	A=0.649
1000Genomes	Europe	Sub	1006	G=0.730	A=0.270
1000Genomes	Global	Study-wide	5008	G=0.460	A=0.540
1000Genomes	South Asian	Sub	978	G=0.640	A=0.360
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.727	A=0.273
The Genome Aggregation Database	African	Sub	8712	G=0.201	A=0.799
The Genome Aggregation Database	American	Sub	838	G=0.650	A=0.350
The Genome Aggregation Database	East Asian	Sub	1608	G=0.320	A=0.680
The Genome Aggregation Database	Europe	Sub	18454	G=0.729	A=0.270
The Genome Aggregation Database	Global	Study-wide	29914	G=0.551	A=0.448
The Genome Aggregation Database	Other	Sub	302	G=0.740	A=0.260
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.465	A=0.534
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.732	A=0.268

PMID	Title	Author	Journal
21314694	Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.	Kendler KS	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs10417874	0.000273	alcohol dependence	21314694

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr19	55623170	55623367	E067	-9026
chr19	55624076	55626358	E067	-6035
chr19	55624076	55626358	E068	-6035
chr19	55609817	55609905	E069	-22488
chr19	55609951	55610018	E069	-22375
chr19	55623923	55624066	E069	-8327
chr19	55624076	55626358	E069	-6035
chr19	55597151	55597214	E070	-35179
chr19	55624076	55626358	E070	-6035
chr19	55611188	55611447	E071	-20946
chr19	55611555	55611798	E071	-20595
chr19	55624076	55626358	E071	-6035
chr19	55612828	55612908	E072	-19485
chr19	55623170	55623367	E072	-9026
chr19	55624076	55626358	E072	-6035
chr19	55652234	55652322	E072	19841
chr19	55612828	55612908	E073	-19485
chr19	55623170	55623367	E073	-9026
chr19	55623457	55623567	E073	-8826
chr19	55623609	55623669	E073	-8724
chr19	55623688	55623864	E073	-8529
chr19	55623923	55624066	E073	-8327
chr19	55624076	55626358	E073	-6035
chr19	55612828	55612908	E074	-19485
chr19	55624076	55626358	E074	-6035
chr19	55624076	55626358	E081	-6035
chr19	55663287	55663664	E082	30894

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr19	55626377	55630737	E067	-1656
chr19	55677198	55678852	E067	44805
chr19	55626377	55630737	E068	-1656
chr19	55677198	55678852	E068	44805
chr19	55626377	55630737	E069	-1656
chr19	55677198	55678852	E069	44805
chr19	55597478	55600536	E070	-31857
chr19	55626377	55630737	E070	-1656
chr19	55677198	55678852	E070	44805
chr19	55597478	55600536	E071	-31857
chr19	55626377	55630737	E071	-1656
chr19	55677198	55678852	E071	44805
chr19	55626377	55630737	E072	-1656
chr19	55667233	55668569	E072	34840
chr19	55677198	55678852	E072	44805
chr19	55626377	55630737	E073	-1656
chr19	55677198	55678852	E073	44805
chr19	55626377	55630737	E074	-1656
chr19	55677198	55678852	E074	44805
chr19	55591298	55594252	E082	-38141
chr19	55597478	55600536	E082	-31857
chr19	55626377	55630737	E082	-1656
chr19	55667233	55668569	E082	34840

rs10417874