rs10423905

Homo sapiens
A>C / A>T
LOC284395 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0352 (10540/29924,GnomAD)
C=0344 (10016/29118,TOPMED)
C=0252 (1262/5008,1000G)
chr19:29437946 (GRCh38.p7) (19q12)
AD
GWASdb2
1   publication(s)
See rs on genome
41 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 19NC_000019.10:g.29437946A>C
GRCh38.p7 chr 19NC_000019.10:g.29437946A>T
GRCh37.p13 chr 19NC_000019.9:g.29928853A>C
GRCh37.p13 chr 19NC_000019.9:g.29928853A>T

Gene: LOC284395, uncharacterized LOC284395(minus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC284395 transcriptNR_040029.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.716C=0.284
1000GenomesAmericanSub694A=0.750C=0.250
1000GenomesEast AsianSub1008A=0.909C=0.091
1000GenomesEuropeSub1006A=0.588C=0.412
1000GenomesGlobalStudy-wide5008A=0.748C=0.252
1000GenomesSouth AsianSub978A=0.790C=0.210
The Genome Aggregation DatabaseAfricanSub8712A=0.715T=0.000
The Genome Aggregation DatabaseAmericanSub838A=0.760T=0.00,
The Genome Aggregation DatabaseEast AsianSub1618A=0.912T=0.000
The Genome Aggregation DatabaseEuropeSub18454A=0.586T=0.000
The Genome Aggregation DatabaseGlobalStudy-wide29924A=0.647T=0.000
The Genome Aggregation DatabaseOtherSub302A=0.730T=0.00,
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.656C=0.344
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs104239050.00054alcohol dependence20201924
rs104239050.00066Alcohol dependence (early age of onset)20201924

eQTL of rs10423905 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10423905 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr194663611846636919E067-33017
chr194663698046637618E067-32318
chr194669701146697176E06727075
chr194669726146697372E06727325
chr194669738846697459E06727452
chr194670613946706227E06736203
chr194670636846707088E06736432
chr194663611846636919E068-33017
chr194663698046637618E068-32318
chr194669256546692697E06822629
chr194669273946693053E06822803
chr194663611846636919E069-33017
chr194663698046637618E069-32318
chr194669256546692697E06922629
chr194669677946696970E06926843
chr194669701146697176E06927075
chr194669726146697372E06927325
chr194670452746705162E06934591
chr194663611846636919E071-33017
chr194663698046637618E071-32318
chr194669677946696970E07126843
chr194669701146697176E07127075
chr194669726146697372E07127325
chr194669738846697459E07127452
chr194670636846707088E07136432
chr194663611846636919E072-33017
chr194663698046637618E072-32318
chr194663785146638078E072-31858
chr194669701146697176E07227075
chr194669726146697372E07227325
chr194669738846697459E07227452
chr194670452746705162E07234591
chr194670636846707088E07236432
chr194663698046637618E073-32318
chr194663611846636919E074-33017
chr194663698046637618E074-32318
chr194669701146697176E07427075
chr194669726146697372E07427325
chr194669738846697459E07427452
chr194670452746705162E07434591
chr194663018446630417E081-39519