SNP Detail Info-rs10425738

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G==0268 (7962/29642,GnomAD)
G==0247 (7207/29118,TOPMED)
G==0248 (1240/5008,1000G)
G==0289 (1113/3854,ALSPAC)
G==0279 (1036/3708,TWINSUK)

Position: chr19:40911822 (GRCh38.p7) (19q13.2)

Phenotype: ND

Dataset:

GWASCatalog

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 1 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 19	NC_000019.10:g.40911822G>A
GRCh37.p13 chr 19	NC_000019.9:g.41417727G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.234	A=0.766
1000Genomes	American	Sub	694	G=0.180	A=0.820
1000Genomes	East Asian	Sub	1008	G=0.290	A=0.710
1000Genomes	Europe	Sub	1006	G=0.253	A=0.747
1000Genomes	Global	Study-wide	5008	G=0.248	A=0.752
1000Genomes	South Asian	Sub	978	G=0.260	A=0.740
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.289	A=0.711
The Genome Aggregation Database	African	Sub	8620	G=0.250	A=0.750
The Genome Aggregation Database	American	Sub	832	G=0.190	A=0.810
The Genome Aggregation Database	East Asian	Sub	1582	G=0.291	A=0.709
The Genome Aggregation Database	Europe	Sub	18308	G=0.278	A=0.721
The Genome Aggregation Database	Global	Study-wide	29642	G=0.268	A=0.731
The Genome Aggregation Database	Other	Sub	300	G=0.300	A=0.700
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.247	A=0.752
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.279	A=0.721

PMID	Title	Author	Journal
27488534	Novel Association of Genetic Markers Affecting CYP2A6 Activity and Lung Cancer Risk.	Patel YM	Cancer Res

SNP ID	p-value	Traits	Study
rs10425738	1E-24	nicotine metabolite ratio in current smokers	27488534

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs10425738