SNP Detail Info-rs10463741

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0164 (4932/29920,GnomAD)
G=0123 (3609/29118,TOPMED)
G=0187 (934/5008,1000G)
G=0195 (750/3854,ALSPAC)
G=0187 (694/3708,TWINSUK)

Position: chr5:121444191 (GRCh38.p7) (5q23.1)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 2 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 5	NC_000005.10:g.121444191A>G
GRCh37.p13 chr 5	NC_000005.9:g.120779886A>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.980	G=0.020
1000Genomes	American	Sub	694	A=0.840	G=0.160
1000Genomes	East Asian	Sub	1008	A=0.501	G=0.499
1000Genomes	Europe	Sub	1006	A=0.814	G=0.186
1000Genomes	Global	Study-wide	5008	A=0.813	G=0.187
1000Genomes	South Asian	Sub	978	A=0.890	G=0.110
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.805	G=0.195
The Genome Aggregation Database	African	Sub	8726	A=0.964	G=0.036
The Genome Aggregation Database	American	Sub	838	A=0.860	G=0.140
The Genome Aggregation Database	East Asian	Sub	1612	A=0.524	G=0.476
The Genome Aggregation Database	Europe	Sub	18442	A=0.800	G=0.199
The Genome Aggregation Database	Global	Study-wide	29920	A=0.835	G=0.164
The Genome Aggregation Database	Other	Sub	302	A=0.820	G=0.180
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.876	G=0.123
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.813	G=0.187

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs10463741	0.0000847	alcoholism	pha002891
rs10463741	0.0000847	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr5	120750901	120751274	E070	-28612
chr5	120751497	120751556	E070	-28330

rs10463741