rs10464815

Homo sapiens
A>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0098 (2955/29950,GnomAD)
C=0101 (2960/29118,TOPMED)
C=0148 (739/5008,1000G)
C=0059 (228/3854,ALSPAC)
C=0048 (178/3708,TWINSUK)
chr8:100795923 (GRCh38.p7) (8q22.3)
AD
GWASdb2
2   publication(s)
See rs on genome
20 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.100795923A>C
GRCh37.p13 chr 8NC_000008.10:g.101808151A>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.854C=0.146
1000GenomesAmericanSub694A=0.810C=0.190
1000GenomesEast AsianSub1008A=0.710C=0.290
1000GenomesEuropeSub1006A=0.948C=0.052
1000GenomesGlobalStudy-wide5008A=0.852C=0.148
1000GenomesSouth AsianSub978A=0.930C=0.070
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.941C=0.059
The Genome Aggregation DatabaseAfricanSub8716A=0.860C=0.140
The Genome Aggregation DatabaseAmericanSub836A=0.810C=0.190
The Genome Aggregation DatabaseEast AsianSub1608A=0.688C=0.312
The Genome Aggregation DatabaseEuropeSub18488A=0.942C=0.057
The Genome Aggregation DatabaseGlobalStudy-wide29950A=0.901C=0.098
The Genome Aggregation DatabaseOtherSub302A=0.950C=0.050
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.898C=0.101
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.952C=0.048
PMID Title Author Journal
21989058Association of 8q22.3 locus in Chinese Han with idiopathic premature ovarian failure (POF).Qin YHum Mol Genet
23743675A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.Kapoor MHum Genet

P-Value

SNP ID p-value Traits Study
rs104648153.43E-05alcohol consumption23743675

eQTL of rs10464815 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10464815 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr8101773554101775046E068-33105
chr8101847470101848214E06839319
chr8101762717101763214E071-44937
chr8101764400101764498E071-43653
chr8101764560101764751E071-43400
chr8101764770101764823E071-43328
chr8101803597101803661E072-4490
chr8101803758101804338E074-3813
chr8101804391101804510E074-3641
chr8101847470101848214E07439319
chr8101848259101848339E07440108
chr8101775773101775823E081-32328
chr8101775832101775882E081-32269
chr8101775951101776079E081-32072
chr8101803597101803661E081-4490
chr8101803758101804338E081-3813
chr8101804391101804510E081-3641
chr8101851627101851825E08143476
chr8101851845101851917E08143694
chr8101775334101775644E082-32507