rs10477601

Homo sapiens
G>A
LOC105379145 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A=0087 (2615/29968,GnomAD)
A=0088 (2572/29118,TOPMED)
A=0078 (391/5008,1000G)
A=0078 (300/3854,ALSPAC)
A=0087 (324/3708,TWINSUK)
chr5:120447866 (GRCh38.p7) (5q23.1)
AD
GWASdb2
1   publication(s)
See rs on genome
5 Enhancers around
29 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.120447866G>A
GRCh37.p13 chr 5NC_000005.9:g.119783561G>A

Gene: LOC105379145, uncharacterized LOC105379145(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC105379145 transcript variant X2XR_001742861.1:n.N/AIntron Variant
LOC105379145 transcript variant X1XR_948708.2:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.860A=0.140
1000GenomesAmericanSub694G=0.940A=0.060
1000GenomesEast AsianSub1008G=0.980A=0.020
1000GenomesEuropeSub1006G=0.918A=0.082
1000GenomesGlobalStudy-wide5008G=0.922A=0.078
1000GenomesSouth AsianSub978G=0.940A=0.060
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.922A=0.078
The Genome Aggregation DatabaseAfricanSub8726G=0.881A=0.119
The Genome Aggregation DatabaseAmericanSub838G=0.950A=0.050
The Genome Aggregation DatabaseEast AsianSub1618G=0.972A=0.028
The Genome Aggregation DatabaseEuropeSub18484G=0.921A=0.078
The Genome Aggregation DatabaseGlobalStudy-wide29968G=0.912A=0.087
The Genome Aggregation DatabaseOtherSub302G=0.920A=0.080
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.911A=0.088
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.913A=0.087
PMID Title Author Journal
23743675A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.Kapoor MHum Genet

P-Value

SNP ID p-value Traits Study
rs104776016.31E-05alcohol consumption23743675

eQTL of rs10477601 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10477601 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr5119798828119799389E06815267
chr5119798828119799389E06915267
chr5119798828119799389E07115267
chr5119798828119799389E07415267
chr5119798828119799389E08115267





Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr5119799407119799500E06715846
chr5119799507119801934E06715946
chr5119802039119802178E06718478
chr5119802184119802382E06718623
chr5119799407119799500E06815846
chr5119799507119801934E06815946
chr5119802039119802178E06818478
chr5119802184119802382E06818623
chr5119793604119794213E06910043
chr5119799507119801934E06915946
chr5119799407119799500E07015846
chr5119799507119801934E07015946
chr5119793604119794213E07110043
chr5119799407119799500E07115846
chr5119799507119801934E07115946
chr5119799507119801934E07215946
chr5119802039119802178E07218478
chr5119802184119802382E07218623
chr5119799507119801934E07315946
chr5119802039119802178E07318478
chr5119802184119802382E07318623
chr5119799407119799500E07415846
chr5119799507119801934E07415946
chr5119799407119799500E08115846
chr5119799507119801934E08115946
chr5119799407119799500E08215846
chr5119799507119801934E08215946
chr5119802039119802178E08218478
chr5119802184119802382E08218623