rs10488719

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0204 (6109/29930,GnomAD)
A=0181 (5289/29118,TOPMED)
A=0208 (1040/5008,1000G)
A=0254 (979/3854,ALSPAC)
A=0262 (972/3708,TWINSUK)
chr11:110877346 (GRCh38.p7) (11q23.1)
AD
GWASdb2
1   publication(s)
See rs on genome
28 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.110877346G>A
GRCh37.p13 chr 11NC_000011.9:g.110748070G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.964A=0.036
1000GenomesAmericanSub694G=0.810A=0.190
1000GenomesEast AsianSub1008G=0.711A=0.289
1000GenomesEuropeSub1006G=0.750A=0.250
1000GenomesGlobalStudy-wide5008G=0.792A=0.208
1000GenomesSouth AsianSub978G=0.680A=0.320
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.746A=0.254
The Genome Aggregation DatabaseAfricanSub8722G=0.931A=0.069
The Genome Aggregation DatabaseAmericanSub838G=0.820A=0.180
The Genome Aggregation DatabaseEast AsianSub1608G=0.736A=0.264
The Genome Aggregation DatabaseEuropeSub18460G=0.736A=0.263
The Genome Aggregation DatabaseGlobalStudy-wide29930G=0.795A=0.204
The Genome Aggregation DatabaseOtherSub302G=0.770A=0.230
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.818A=0.181
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.738A=0.262
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs104887190.00065alcohol dependence20201924

eQTL of rs10488719 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10488719 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr11110753966110754395E0675896
chr11110790072110790717E06742002
chr11110771659110771709E06823589
chr11110772818110772868E06824748
chr11110773061110773194E06824991
chr11110778147110778891E06830077
chr11110778904110778970E06830834
chr11110778975110779033E06830905
chr11110779091110779144E06831021
chr11110779237110779812E06831167
chr11110789785110789835E06841715
chr11110790072110790717E06842002
chr11110753753110753803E0695683
chr11110753966110754395E0695896
chr11110754465110754618E0696395
chr11110790072110790717E06942002
chr11110753966110754395E0715896
chr11110789785110789835E07141715
chr11110753966110754395E0745896
chr11110754465110754618E0746395
chr11110789083110789338E08141013
chr11110789785110789835E08141715
chr11110790072110790717E08142002
chr11110791560110791610E08143490
chr11110791978110792065E08143908
chr11110792077110792212E08144007
chr11110792355110793036E08144285
chr11110792355110793036E08244285