rs10490672

Homo sapiens
A>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0062 (1872/29978,GnomAD)
C=0092 (2684/29116,TOPMED)
C=0063 (317/5008,1000G)
C=0001 (2/3854,ALSPAC)
C=0000 (0/3708,TWINSUK)
chr2:36343996 (GRCh38.p7) (2p22.2)
AD
GWASdb2
1   publication(s)
See rs on genome
160 Enhancers around
19 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.36343996A>C
GRCh37.p13 chr 2NC_000002.11:g.36571139A>C
GRCh38.p7 chr 2 alt locus HSCHR2_1_CTG5NW_003315908.1:g.19284T>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.783C=0.217
1000GenomesAmericanSub694A=0.970C=0.030
1000GenomesEast AsianSub1008A=0.999C=0.001
1000GenomesEuropeSub1006A=0.996C=0.004
1000GenomesGlobalStudy-wide5008A=0.937C=0.063
1000GenomesSouth AsianSub978A=1.000C=0.000
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.999C=0.001
The Genome Aggregation DatabaseAfricanSub8718A=0.788C=0.212
The Genome Aggregation DatabaseAmericanSub838A=0.980C=0.020
The Genome Aggregation DatabaseEast AsianSub1622A=1.000C=0.000
The Genome Aggregation DatabaseEuropeSub18498A=0.999C=0.000
The Genome Aggregation DatabaseGlobalStudy-wide29978A=0.937C=0.062
The Genome Aggregation DatabaseOtherSub302A=1.000C=0.000
Trans-Omics for Precision MedicineGlobalStudy-wide29116A=0.907C=0.092
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=1.000C=0.000
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs104906720.000614alcohol dependence21314694

eQTL of rs10490672 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10490672 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr23658728636587500E06716147
chr23658756936587673E06716430
chr23658777036587857E06716631
chr23658808336588272E06716944
chr23658838636588565E06717247
chr23658858036589254E06717441
chr23658944136589741E06718302
chr23659362636594084E06722487
chr23659411936594227E06722980
chr23659649536596651E06725356
chr23659691136597142E06725772
chr23659818736598807E06727048
chr23659883636599058E06727697
chr23659916436599530E06728025
chr23660021836600680E06729079
chr23660073036600828E06729591
chr23660087136601242E06729732
chr23657962436579747E0688485
chr23657975536580211E0688616
chr23658023536580400E0689096
chr23658043236580704E0689293
chr23658117136581221E06810032
chr23658631536586451E06815176
chr23658652936586690E06815390
chr23658756936587673E06816430
chr23658777036587857E06816631
chr23658808336588272E06816944
chr23658838636588565E06817247
chr23658858036589254E06817441
chr23658944136589741E06818302
chr23659362636594084E06822487
chr23659411936594227E06822980
chr23659459436595509E06823455
chr23659649536596651E06825356
chr23659691136597142E06825772
chr23659757036597660E06826431
chr23659818736598807E06827048
chr23659883636599058E06827697
chr23659916436599530E06828025
chr23660021836600680E06829079
chr23660073036600828E06829591
chr23660087136601242E06829732
chr23660333436604496E06832195
chr23661615436616709E06845015
chr23661674236617029E06845603
chr23662009436620310E06848955
chr23662088236620943E06849743
chr23662097236621077E06849833
chr23655773636558025E069-13114
chr23657975536580211E0698616
chr23658023536580400E0699096
chr23658043236580704E0699293
chr23658117136581221E06910032
chr23658130336581417E06910164
chr23658631536586451E06915176
chr23658652936586690E06915390
chr23658697036587070E06915831
chr23658707536587165E06915936
chr23658858036589254E06917441
chr23658944136589741E06918302
chr23659649536596651E06925356
chr23659691136597142E06925772
chr23659757036597660E06926431
chr23659818736598807E06927048
chr23660317936603331E06932040
chr23660333436604496E06932195
chr23658023536580400E0719096
chr23658043236580704E0719293
chr23658117136581221E07110032
chr23658130336581417E07110164
chr23658631536586451E07115176
chr23658838636588565E07117247
chr23658858036589254E07117441
chr23658944136589741E07118302
chr23659649536596651E07125356
chr23659691136597142E07125772
chr23659757036597660E07126431
chr23659818736598807E07127048
chr23660317936603331E07132040
chr23660333436604496E07132195
chr23662088236620943E07149743
chr23662097236621077E07149833
chr23658130336581417E07210164
chr23658631536586451E07215176
chr23658652936586690E07215390
chr23659649536596651E07225356
chr23659691136597142E07225772
chr23659757036597660E07226431
chr23659818736598807E07227048
chr23659883636599058E07227697
chr23660317936603331E07232040
chr23660333436604496E07232195
chr23658043236580704E0739293
chr23658117136581221E07310032
chr23658631536586451E07315176
chr23658652936586690E07315390
chr23658944136589741E07318302
chr23659106736591230E07319928
chr23659157736591641E07320438
chr23659459436595509E07323455
chr23659552136595704E07324382
chr23659649536596651E07325356
chr23659691136597142E07325772
chr23659757036597660E07326431
chr23659818736598807E07327048
chr23660021836600680E07329079
chr23660073036600828E07329591
chr23660317936603331E07332040
chr23660333436604496E07332195
chr23661615436616709E07345015
chr23657962436579747E0748485
chr23657975536580211E0748616
chr23658023536580400E0749096
chr23658043236580704E0749293
chr23658117136581221E07410032
chr23658130336581417E07410164
chr23658777036587857E07416631
chr23658808336588272E07416944
chr23658838636588565E07417247
chr23658858036589254E07417441
chr23659362636594084E07422487
chr23659649536596651E07425356
chr23659691136597142E07425772
chr23659818736598807E07427048
chr23659883636599058E07427697
chr23660333436604496E07432195
chr23662088236620943E07449743
chr23658130336581417E08110164
chr23658631536586451E08115176
chr23658652936586690E08115390
chr23658697036587070E08115831
chr23658707536587165E08115936
chr23658728636587500E08116147
chr23658756936587673E08116430
chr23658777036587857E08116631
chr23658808336588272E08116944
chr23658858036589254E08117441
chr23660184636602030E08130707
chr23660333436604496E08132195
chr23658043236580704E0829293
chr23658631536586451E08215176
chr23658652936586690E08215390
chr23658697036587070E08215831
chr23658707536587165E08215936
chr23658728636587500E08216147
chr23658756936587673E08216430
chr23658777036587857E08216631
chr23658808336588272E08216944
chr23658838636588565E08217247
chr23658858036589254E08217441
chr23659459436595509E08223455
chr23659552136595704E08224382
chr23659574936595847E08224610
chr23660073036600828E08229591
chr23660087136601242E08229732
chr23661286436613111E08241725
chr23661573436616107E08244595
chr23661615436616709E08245015
chr23661674236617029E08245603
chr23662088236620943E08249743









Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr23658191936583857E06710780
chr23658385936585840E06712720
chr23658191936583857E06810780
chr23658385936585840E06812720
chr23658191936583857E06910780
chr23658385936585840E06912720
chr23658191936583857E07010780
chr23658385936585840E07012720
chr23658191936583857E07110780
chr23658385936585840E07112720
chr23658191936583857E07210780
chr23658385936585840E07212720
chr23658191936583857E07310780
chr23658385936585840E07312720
chr23658191936583857E07410780
chr23658385936585840E07412720
chr23658385936585840E08112720
chr23658191936583857E08210780
chr23658385936585840E08212720