rs10496966

Homo sapiens
A>G
TEX41 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A==0397 (11853/29860,GnomAD)
A==0405 (11813/29118,TOPMED)
A==0373 (1867/5008,1000G)
A==0335 (1293/3854,ALSPAC)
A==0330 (1225/3708,TWINSUK)
chr2:144701195 (GRCh38.p7) (2q22.3)
AD
GWASdb2
1   publication(s)
See rs on genome
19 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.144701195A>G
GRCh37.p13 chr 2NC_000002.11:g.145458762A>G

Gene: TEX41, testis expressed 41 (non-protein coding)(plus strand)

Molecule type Change Amino acid[Codon] SO Term
TEX41 transcriptNR_033870.2:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.599G=0.401
1000GenomesAmericanSub694A=0.280G=0.720
1000GenomesEast AsianSub1008A=0.221G=0.779
1000GenomesEuropeSub1006A=0.351G=0.649
1000GenomesGlobalStudy-wide5008A=0.373G=0.627
1000GenomesSouth AsianSub978A=0.310G=0.690
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.335G=0.665
The Genome Aggregation DatabaseAfricanSub8692A=0.552G=0.448
The Genome Aggregation DatabaseAmericanSub836A=0.230G=0.770
The Genome Aggregation DatabaseEast AsianSub1578A=0.195G=0.805
The Genome Aggregation DatabaseEuropeSub18452A=0.349G=0.650
The Genome Aggregation DatabaseGlobalStudy-wide29860A=0.397G=0.603
The Genome Aggregation DatabaseOtherSub302A=0.330G=0.670
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.405G=0.594
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.330G=0.670
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs104969660.000804alcohol consumption (maxi-drinks)24277619

eQTL of rs10496966 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10496966 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr2145439933145440509E067-18253
chr2145440773145440906E067-17856
chr2145465725145465850E0676963
chr2145465725145465850E0686963
chr2145465725145465850E0696963
chr2145466243145466529E0697481
chr2145465725145465850E0706963
chr2145465366145465700E0716604
chr2145466243145466529E0717481
chr2145465725145465850E0726963
chr2145466243145466529E0727481
chr2145465366145465700E0746604
chr2145465725145465850E0746963
chr2145466243145466529E0747481
chr2145469196145469276E08110434
chr2145469357145469673E08110595
chr2145469778145470030E08111016
chr2145465366145465700E0826604
chr2145465725145465850E0826963