rs10502685

Homo sapiens
C>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0119 (3563/29926,GnomAD)
A=0120 (3501/29118,TOPMED)
A=0097 (487/5008,1000G)
A=0143 (552/3854,ALSPAC)
A=0166 (616/3708,TWINSUK)
chr18:38098747 (GRCh38.p7) (18q12.2)
AD
GWASdb2
1   publication(s)
See rs on genome
4 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 18NC_000018.10:g.38098747C>A
GRCh37.p13 chr 18NC_000018.9:g.35678711C>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.947A=0.053
1000GenomesAmericanSub694C=0.920A=0.080
1000GenomesEast AsianSub1008C=0.984A=0.016
1000GenomesEuropeSub1006C=0.834A=0.166
1000GenomesGlobalStudy-wide5008C=0.903A=0.097
1000GenomesSouth AsianSub978C=0.810A=0.190
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.857A=0.143
The Genome Aggregation DatabaseAfricanSub8714C=0.936A=0.064
The Genome Aggregation DatabaseAmericanSub836C=0.930A=0.070
The Genome Aggregation DatabaseEast AsianSub1610C=0.989A=0.011
The Genome Aggregation DatabaseEuropeSub18464C=0.845A=0.155
The Genome Aggregation DatabaseGlobalStudy-wide29926C=0.880A=0.119
The Genome Aggregation DatabaseOtherSub302C=0.790A=0.210
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.879A=0.120
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.834A=0.166
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs105026850.0006alcohol dependence20201924

eQTL of rs10502685 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10502685 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr183566800035668050E070-10661
chr183566832435668374E070-10337
chr183564678635648258E081-30453
chr183564839435648444E081-30267