rs10504065

Homo sapiens
C>T
LOC101929268 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0039 (1180/29968,GnomAD)
T=0033 (978/29118,TOPMED)
T=0047 (236/5008,1000G)
T=0054 (207/3854,ALSPAC)
T=0048 (178/3708,TWINSUK)
chr8:48572345 (GRCh38.p7) (8q11.21)
AD
GWASdb2
1   publication(s)
See rs on genome
35 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.48572345C>T
GRCh37.p13 chr 8NC_000008.10:g.49484905C>T

Gene: LOC101929268, uncharacterized LOC101929268(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC101929268 transcriptNR_105002.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.999T=0.001
1000GenomesAmericanSub694C=0.970T=0.030
1000GenomesEast AsianSub1008C=0.984T=0.016
1000GenomesEuropeSub1006C=0.950T=0.050
1000GenomesGlobalStudy-wide5008C=0.953T=0.047
1000GenomesSouth AsianSub978C=0.850T=0.150
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.946T=0.054
The Genome Aggregation DatabaseAfricanSub8720C=0.992T=0.008
The Genome Aggregation DatabaseAmericanSub836C=0.970T=0.030
The Genome Aggregation DatabaseEast AsianSub1622C=0.980T=0.020
The Genome Aggregation DatabaseEuropeSub18488C=0.943T=0.056
The Genome Aggregation DatabaseGlobalStudy-wide29968C=0.960T=0.039
The Genome Aggregation DatabaseOtherSub302C=0.970T=0.030
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.966T=0.033
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.952T=0.048
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs105040650.00098alcohol dependence20201924

eQTL of rs10504065 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10504065 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr84946076949460833E068-24072
chr84946093949461019E068-23886
chr84946276249463854E070-21051
chr84953089349531201E07045988
chr84953133749531541E07046432
chr84953161549531669E07046710
chr84953170349531926E07046798
chr84953215749534246E07047252
chr84953426249534715E07049357
chr84944828549449134E081-35771
chr84944922049449590E081-35315
chr84946181549461874E081-23031
chr84946245149462537E081-22368
chr84946262449462712E081-22193
chr84946276249463854E081-21051
chr84946388249464068E081-20837
chr84946410849464300E081-20605
chr84946483749464881E081-20024
chr84946528249465376E081-19529
chr84946540949465459E081-19446
chr84946549049465541E081-19364
chr84946566149465776E081-19129
chr84946597249466049E081-18856
chr84946620949466378E081-18527
chr84946643549470720E081-14185
chr84949262649496781E0817721
chr84953215749534246E08147252
chr84953426249534715E08149357
chr84943632549436607E082-48298
chr84946181549461874E082-23031
chr84946245149462537E082-22368
chr84946262449462712E082-22193
chr84946276249463854E082-21051
chr84946643549470720E082-14185
chr84953215749534246E08247252