rs10504702

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0126 (3788/29962,GnomAD)
A=0145 (4223/29118,TOPMED)
A=0220 (1101/5008,1000G)
A=0100 (385/3854,ALSPAC)
A=0090 (335/3708,TWINSUK)
chr8:79299014 (GRCh38.p7) (8q21.13)
AD
GWASdb2
1   publication(s)
See rs on genome
14 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.79299014G>A
GRCh37.p13 chr 8NC_000008.10:g.80211249G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.782A=0.218
1000GenomesAmericanSub694G=0.840A=0.160
1000GenomesEast AsianSub1008G=0.591A=0.409
1000GenomesEuropeSub1006G=0.918A=0.082
1000GenomesGlobalStudy-wide5008G=0.780A=0.220
1000GenomesSouth AsianSub978G=0.790A=0.210
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.900A=0.100
The Genome Aggregation DatabaseAfricanSub8718G=0.822A=0.178
The Genome Aggregation DatabaseAmericanSub834G=0.850A=0.150
The Genome Aggregation DatabaseEast AsianSub1620G=0.610A=0.390
The Genome Aggregation DatabaseEuropeSub18488G=0.921A=0.078
The Genome Aggregation DatabaseGlobalStudy-wide29962G=0.873A=0.126
The Genome Aggregation DatabaseOtherSub302G=0.920A=0.080
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.855A=0.145
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.910A=0.090
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs105047020.000829alcohol consumption (maxi-drinks)24277619

eQTL of rs10504702 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10504702 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr88022028580220462E0709036
chr88022050680220618E0709257
chr88022094580220989E0709696
chr88022124380221831E0709994
chr88023643380236488E07025184
chr88023699580237331E07025746
chr88024701880247101E07035769
chr88020016180200589E081-10660
chr88020070980200753E081-10496
chr88020091680201020E081-10229
chr88020118380201225E081-10024
chr88020132480201406E081-9843
chr88020142480202491E081-8758
chr88023075080230800E08119501