rs10505382

Homo sapiens
T>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0131 (3931/29972,GnomAD)
G=0142 (4146/29118,TOPMED)
G=0120 (600/5008,1000G)
G=0146 (564/3854,ALSPAC)
G=0139 (515/3708,TWINSUK)
chr8:120916129 (GRCh38.p7) (8q24.12)
ND
GWASdb2
1   publication(s)
See rs on genome
35 Enhancers around
1 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.120916129T>G
GRCh37.p13 chr 8NC_000008.10:g.121928369T>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.849G=0.151
1000GenomesAmericanSub694T=0.910G=0.090
1000GenomesEast AsianSub1008T=0.964G=0.036
1000GenomesEuropeSub1006T=0.857G=0.143
1000GenomesGlobalStudy-wide5008T=0.880G=0.120
1000GenomesSouth AsianSub978T=0.840G=0.160
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.854G=0.146
The Genome Aggregation DatabaseAfricanSub8726T=0.847G=0.153
The Genome Aggregation DatabaseAmericanSub838T=0.900G=0.100
The Genome Aggregation DatabaseEast AsianSub1616T=0.973G=0.027
The Genome Aggregation DatabaseEuropeSub18490T=0.869G=0.130
The Genome Aggregation DatabaseGlobalStudy-wide29972T=0.868G=0.131
The Genome Aggregation DatabaseOtherSub302T=0.820G=0.180
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.857G=0.142
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.861G=0.139
PMID Title Author Journal
20158304A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.Lind PATwin Res Hum Genet

P-Value

SNP ID p-value Traits Study
rs105053829.1E-07alcohol and nictotine co-dependence20158304

eQTL of rs10505382 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10505382 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr8121945002121945454E06816633
chr8121945502121945872E06817133
chr8121945920121946003E06817551
chr8121946044121946162E06817675
chr8121946193121946251E06817824
chr8121945502121945872E06917133
chr8121945920121946003E06917551
chr8121919698121920098E070-8271
chr8121972229121973105E07043860
chr8121945002121945454E07116633
chr8121945502121945872E07117133
chr8121945920121946003E07117551
chr8121946044121946162E07117675
chr8121946193121946251E07117824
chr8121945002121945454E07216633
chr8121945502121945872E07217133
chr8121945920121946003E07217551
chr8121946044121946162E07217675
chr8121946193121946251E07217824
chr8121945002121945454E07316633
chr8121945502121945872E07317133
chr8121945920121946003E07317551
chr8121945002121945454E07416633
chr8121945502121945872E07417133
chr8121945920121946003E07417551
chr8121965369121965461E08137000
chr8121965509121965563E08137140
chr8121965682121965737E08137313
chr8121965937121966187E08137568
chr8121967350121967436E08138981
chr8121967861121968080E08139492
chr8121949997121950051E08221628
chr8121950076121950624E08221707
chr8121971849121972024E08243480
chr8121972229121973105E08243860









Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr8121880879121881427E068-46942