rs10505560

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0138 (4145/29946,GnomAD)
C=0136 (3969/29118,TOPMED)
C=0168 (840/5008,1000G)
C=0193 (742/3854,ALSPAC)
C=0197 (730/3708,TWINSUK)
chr8:130732742 (GRCh38.p7) (8q24.22)
AD
GWASdb2
1   publication(s)
See rs on genome
23 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.130732742T>C
GRCh37.p13 chr 8NC_000008.10:g.131744988T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.970C=0.030
1000GenomesAmericanSub694T=0.870C=0.130
1000GenomesEast AsianSub1008T=0.781C=0.219
1000GenomesEuropeSub1006T=0.783C=0.217
1000GenomesGlobalStudy-wide5008T=0.832C=0.168
1000GenomesSouth AsianSub978T=0.720C=0.280
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.807C=0.193
The Genome Aggregation DatabaseAfricanSub8730T=0.948C=0.052
The Genome Aggregation DatabaseAmericanSub836T=0.900C=0.100
The Genome Aggregation DatabaseEast AsianSub1604T=0.756C=0.244
The Genome Aggregation DatabaseEuropeSub18476T=0.829C=0.170
The Genome Aggregation DatabaseGlobalStudy-wide29946T=0.861C=0.138
The Genome Aggregation DatabaseOtherSub300T=0.770C=0.230
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.863C=0.136
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.803C=0.197
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs105055600.00074alcohol dependence21314694

eQTL of rs10505560 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10505560 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr8131695392131695499E067-49489
chr8131696148131696453E067-48535
chr8131696148131696453E068-48535
chr8131696496131696577E068-48411
chr8131695275131695375E069-49613
chr8131695392131695499E069-49489
chr8131696148131696453E069-48535
chr8131696496131696577E069-48411
chr8131696148131696453E070-48535
chr8131696496131696577E070-48411
chr8131761780131762349E07016792
chr8131774088131774886E07029100
chr8131695275131695375E071-49613
chr8131695392131695499E071-49489
chr8131696148131696453E071-48535
chr8131696496131696577E071-48411
chr8131739299131740179E071-4809
chr8131696148131696453E072-48535
chr8131696496131696577E072-48411
chr8131695275131695375E073-49613
chr8131695392131695499E073-49489
chr8131696148131696453E074-48535
chr8131696496131696577E074-48411