rs10511022

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0342 (10255/29924,GnomAD)
C==0433 (12623/29118,TOPMED)
C==0383 (1918/5008,1000G)
C==0210 (810/3854,ALSPAC)
C==0203 (752/3708,TWINSUK)
chr3:72495045 (GRCh38.p7) (3p13)
ND
GWASdb2
1   publication(s)
See rs on genome
71 Enhancers around
20 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.72495045C>T
GRCh37.p13 chr 3NC_000003.11:g.72544196C>T
GRCh38.p7 chr 3 fix patch HG126_PATCHNW_011332691.1:g.169987T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.793T=0.207
1000GenomesAmericanSub694C=0.260T=0.740
1000GenomesEast AsianSub1008C=0.239T=0.761
1000GenomesEuropeSub1006C=0.216T=0.784
1000GenomesGlobalStudy-wide5008C=0.383T=0.617
1000GenomesSouth AsianSub978C=0.240T=0.760
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.210T=0.790
The Genome Aggregation DatabaseAfricanSub8694C=0.698T=0.302
The Genome Aggregation DatabaseAmericanSub834C=0.210T=0.790
The Genome Aggregation DatabaseEast AsianSub1616C=0.233T=0.767
The Genome Aggregation DatabaseEuropeSub18478C=0.192T=0.807
The Genome Aggregation DatabaseGlobalStudy-wide29924C=0.342T=0.657
The Genome Aggregation DatabaseOtherSub302C=0.240T=0.760
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.433T=0.566
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.203T=0.797
PMID Title Author Journal
20158304A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.Lind PATwin Res Hum Genet

P-Value

SNP ID p-value Traits Study
rs105110222.24E-05alcohol and nictotine co-dependence20158304

eQTL of rs10511022 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10511022 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr37249719672497334E067-46862
chr37251473572515000E067-29196
chr37251503972515199E067-28997
chr37251522272515315E067-28881
chr37251535672515476E067-28720
chr37253995672540191E067-4005
chr37254025272540533E067-3663
chr37249719672497334E068-46862
chr37249734772497621E068-46575
chr37249768472498014E068-46182
chr37251473572515000E068-29196
chr37251503972515199E068-28997
chr37251522272515315E068-28881
chr37251535672515476E068-28720
chr37253476372535210E068-8986
chr37253524672535329E068-8867
chr37253995672540191E068-4005
chr37254025272540533E068-3663
chr37249734772497621E069-46575
chr37249768472498014E069-46182
chr37251156772512074E069-32122
chr37251473572515000E069-29196
chr37251503972515199E069-28997
chr37251522272515315E069-28881
chr37251535672515476E069-28720
chr37253995672540191E069-4005
chr37254025272540533E069-3663
chr37254138772541850E069-2346
chr37251473572515000E070-29196
chr37251503972515199E070-28997
chr37251522272515315E070-28881
chr37251535672515476E070-28720
chr37258495672585277E07040760
chr37258528872585575E07041092
chr37249719672497334E071-46862
chr37249734772497621E071-46575
chr37249768472498014E071-46182
chr37251111572511264E071-32932
chr37251156772512074E071-32122
chr37251473572515000E071-29196
chr37251503972515199E071-28997
chr37251522272515315E071-28881
chr37251535672515476E071-28720
chr37253476372535210E071-8986
chr37253524672535329E071-8867
chr37253995672540191E071-4005
chr37254025272540533E071-3663
chr37249719672497334E072-46862
chr37249734772497621E072-46575
chr37249768472498014E072-46182
chr37251473572515000E072-29196
chr37251503972515199E072-28997
chr37251522272515315E072-28881
chr37251535672515476E072-28720
chr37253995672540191E072-4005
chr37254025272540533E072-3663
chr37254138772541850E072-2346
chr37249768472498014E073-46182
chr37251473572515000E073-29196
chr37251503972515199E073-28997
chr37251522272515315E073-28881
chr37251535672515476E073-28720
chr37249719672497334E074-46862
chr37249734772497621E074-46575
chr37249768472498014E074-46182
chr37249809372498360E074-45836
chr37253995672540191E074-4005
chr37254025272540533E074-3663
chr37254138772541850E074-2346
chr37249719672497334E081-46862
chr37259360572593655E08249409










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr37249463172495273E067-48923
chr37249529072497147E067-47049
chr37249463172495273E068-48923
chr37249529072497147E068-47049
chr37249463172495273E069-48923
chr37249529072497147E069-47049
chr37249463172495273E070-48923
chr37249529072497147E070-47049
chr37249463172495273E071-48923
chr37249529072497147E071-47049
chr37249463172495273E072-48923
chr37249529072497147E072-47049
chr37249463172495273E073-48923
chr37249529072497147E073-47049
chr37249463172495273E074-48923
chr37249529072497147E074-47049
chr37249463172495273E081-48923
chr37249529072497147E081-47049
chr37249463172495273E082-48923
chr37249529072497147E082-47049