rs10514712

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0159 (4774/29964,GnomAD)
C=0148 (4334/29118,TOPMED)
C=0157 (784/5008,1000G)
C=0225 (867/3854,ALSPAC)
C=0229 (848/3708,TWINSUK)
chr3:45042436 (GRCh38.p7) (3p21.31)
ND
GWASdb2
1   publication(s)
See rs on genome
107 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.45042436T>C
GRCh37.p13 chr 3NC_000003.11:g.45083928T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.954C=0.046
1000GenomesAmericanSub694T=0.730C=0.270
1000GenomesEast AsianSub1008T=0.909C=0.091
1000GenomesEuropeSub1006T=0.751C=0.249
1000GenomesGlobalStudy-wide5008T=0.843C=0.157
1000GenomesSouth AsianSub978T=0.800C=0.200
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.775C=0.225
The Genome Aggregation DatabaseAfricanSub8724T=0.935C=0.065
The Genome Aggregation DatabaseAmericanSub838T=0.730C=0.270
The Genome Aggregation DatabaseEast AsianSub1622T=0.911C=0.089
The Genome Aggregation DatabaseEuropeSub18480T=0.797C=0.202
The Genome Aggregation DatabaseGlobalStudy-wide29964T=0.840C=0.159
The Genome Aggregation DatabaseOtherSub300T=0.720C=0.280
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.851C=0.148
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.771C=0.229
PMID Title Author Journal
20158304A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.Lind PATwin Res Hum Genet

P-Value

SNP ID p-value Traits Study
rs105147128.07E-05alcohol and nictotine co-dependence20158304

eQTL of rs10514712 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10514712 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr34503749545037563E067-46365
chr34503776945037843E067-46085
chr34507822445078365E067-5563
chr34503494145035685E068-48243
chr34503617245036293E068-47635
chr34503683745037258E068-46670
chr34503749545037563E068-46365
chr34505884045059047E068-24881
chr34505905245059106E068-24822
chr34505914445059228E068-24700
chr34505927645059720E068-24208
chr34506266745062717E068-21211
chr34506273545063647E068-20281
chr34506599245066380E068-17548
chr34506638445066646E068-17282
chr34506672145066920E068-17008
chr34506849245068786E068-15142
chr34507611645076808E068-7120
chr34507798145078099E068-5829
chr34507822445078365E068-5563
chr34507845045078938E068-4990
chr34507918545079957E068-3971
chr34510206645102215E06818138
chr34510229845102520E06818370
chr34505229845054120E069-29808
chr34505412645054334E069-29594
chr34506693945067083E069-16845
chr34506717845067278E069-16650
chr34507822445078365E070-5563
chr34507845045078938E070-4990
chr34510206645102215E07018138
chr34510229845102520E07018370
chr34503494145035685E071-48243
chr34503617245036293E071-47635
chr34503683745037258E071-46670
chr34503749545037563E071-46365
chr34505229845054120E071-29808
chr34505412645054334E071-29594
chr34506208945062424E071-21504
chr34506247345062548E071-21380
chr34506254945062600E071-21328
chr34506266745062717E071-21211
chr34506273545063647E071-20281
chr34506599245066380E071-17548
chr34506638445066646E071-17282
chr34506672145066920E071-17008
chr34506693945067083E071-16845
chr34506717845067278E071-16650
chr34506849245068786E071-15142
chr34507540545075510E071-8418
chr34507565945075746E071-8182
chr34507611645076808E071-7120
chr34507689545077007E071-6921
chr34507706545077144E071-6784
chr34507798145078099E071-5829
chr34507822445078365E071-5563
chr34507845045078938E071-4990
chr34510206645102215E07118138
chr34510229845102520E07118370
chr34503683745037258E072-46670
chr34503749545037563E072-46365
chr34503776945037843E072-46085
chr34507798145078099E072-5829
chr34507822445078365E072-5563
chr34503494145035685E073-48243
chr34503617245036293E073-47635
chr34503683745037258E073-46670
chr34503749545037563E073-46365
chr34505412645054334E073-29594
chr34506019945060268E073-23660
chr34506599245066380E073-17548
chr34506638445066646E073-17282
chr34506672145066920E073-17008
chr34506693945067083E073-16845
chr34506717845067278E073-16650
chr34507080945070904E073-13024
chr34507540545075510E073-8418
chr34507565945075746E073-8182
chr34507611645076808E073-7120
chr34507689545077007E073-6921
chr34507798145078099E073-5829
chr34507822445078365E073-5563
chr34507845045078938E073-4990
chr34503494145035685E074-48243
chr34503617245036293E074-47635
chr34503683745037258E074-46670
chr34503749545037563E074-46365
chr34503776945037843E074-46085
chr34503795645038546E074-45382
chr34506599245066380E074-17548
chr34506638445066646E074-17282
chr34506672145066920E074-17008
chr34506693945067083E074-16845
chr34506717845067278E074-16650
chr34507540545075510E074-8418
chr34507565945075746E074-8182
chr34507798145078099E074-5829
chr34507822445078365E074-5563
chr34509819345098757E07414265
chr34506208945062424E081-21504
chr34507689545077007E081-6921
chr34507706545077144E081-6784
chr34507798145078099E081-5829
chr34507822445078365E081-5563
chr34507845045078938E081-4990
chr34507798145078099E082-5829
chr34507822445078365E082-5563