rs10515737

Homo sapiens
A>C
SGCD : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0028 (850/29990,GnomAD)
C=0028 (821/29118,TOPMED)
C=0055 (273/5008,1000G)
C=0002 (9/3854,ALSPAC)
C=0002 (9/3708,TWINSUK)
chr5:156595519 (GRCh38.p7) (5q33.3)
AD
GWASdb2
1   publication(s)
See rs on genome
117 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.156595519A>C
GRCh37.p13 chr 5NC_000005.9:g.156022529A>C
SGCD RefSeqGene LRG_205

Gene: SGCD, sarcoglycan delta(plus strand)

Molecule type Change Amino acid[Codon] SO Term
SGCD transcript variant 1NM_000337.5:c.N/AIntron Variant
SGCD transcript variant 3NM_001128209.1:c.N/AIntron Variant
SGCD transcript variant 2NM_172244.2:c.N/AIntron Variant
SGCD transcript variant X3XM_005265966.4:c.N/AIntron Variant
SGCD transcript variant X5XM_005265967.2:c.N/AIntron Variant
SGCD transcript variant X4XM_011534621.2:c.N/AIntron Variant
SGCD transcript variant X1XM_017009723.1:c.N/AIntron Variant
SGCD transcript variant X2XM_017009724.1:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.943C=0.057
1000GenomesAmericanSub694A=0.990C=0.010
1000GenomesEast AsianSub1008A=0.823C=0.177
1000GenomesEuropeSub1006A=0.996C=0.004
1000GenomesGlobalStudy-wide5008A=0.945C=0.055
1000GenomesSouth AsianSub978A=0.990C=0.010
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.998C=0.002
The Genome Aggregation DatabaseAfricanSub8732A=0.941C=0.059
The Genome Aggregation DatabaseAmericanSub838A=0.980C=0.020
The Genome Aggregation DatabaseEast AsianSub1614A=0.823C=0.177
The Genome Aggregation DatabaseEuropeSub18506A=0.997C=0.002
The Genome Aggregation DatabaseGlobalStudy-wide29990A=0.971C=0.028
The Genome Aggregation DatabaseOtherSub300A=1.000C=0.000
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.971C=0.028
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.998C=0.002
PMID Title Author Journal

P-Value

SNP ID p-value Traits Study
rs105157377.33E-65alcohol consumptionpha001402
rs105157374.71E-37alcohol consumptionpha001400
rs105157377.27E-11alcohol consumptionpha001398

eQTL of rs10515737 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10515737 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr5155984141155984446E067-38083
chr5156009212156009407E067-13122
chr5156009518156009583E067-12946
chr5156011319156011639E067-10890
chr5156011651156012061E067-10468
chr5156012073156012199E067-10330
chr5156012525156012619E067-9910
chr5156012723156012818E067-9711
chr5156013695156013862E067-8667
chr5156014194156014267E067-8262
chr5156015144156015335E067-7194
chr5156015383156016032E067-6497
chr5156016149156016435E067-6094
chr5156016439156016881E067-5648
chr5156018022156018965E067-3564
chr5156022296156022376E067-153
chr5156022452156022824E0670
chr5156022977156023092E067448
chr5156050488156050627E06727959
chr5156050775156050832E06728246
chr5155984141155984446E068-38083
chr5156009212156009407E068-13122
chr5156009518156009583E068-12946
chr5156012073156012199E068-10330
chr5156012525156012619E068-9910
chr5156012723156012818E068-9711
chr5156013695156013862E068-8667
chr5156014194156014267E068-8262
chr5156015383156016032E068-6497
chr5156016149156016435E068-6094
chr5156018022156018965E068-3564
chr5156050488156050627E06827959
chr5156050775156050832E06828246
chr5155984141155984446E069-38083
chr5156011319156011639E069-10890
chr5156011651156012061E069-10468
chr5156012073156012199E069-10330
chr5156012525156012619E069-9910
chr5156012723156012818E069-9711
chr5156013695156013862E069-8667
chr5156014194156014267E069-8262
chr5156015144156015335E069-7194
chr5156015383156016032E069-6497
chr5156016149156016435E069-6094
chr5156016439156016881E069-5648
chr5156018022156018965E069-3564
chr5156022452156022824E0690
chr5156022977156023092E069448
chr5156050488156050627E06927959
chr5156050775156050832E06928246
chr5155987015155987362E070-35167
chr5155984141155984446E071-38083
chr5156009212156009407E071-13122
chr5156009518156009583E071-12946
chr5156011319156011639E071-10890
chr5156011651156012061E071-10468
chr5156012073156012199E071-10330
chr5156012525156012619E071-9910
chr5156012723156012818E071-9711
chr5156013695156013862E071-8667
chr5156014194156014267E071-8262
chr5156015383156016032E071-6497
chr5156016149156016435E071-6094
chr5156016439156016881E071-5648
chr5156018022156018965E071-3564
chr5156022296156022376E071-153
chr5156022452156022824E0710
chr5156026001156026271E0713472
chr5156050775156050832E07128246
chr5156009518156009583E072-12946
chr5156011651156012061E072-10468
chr5156012073156012199E072-10330
chr5156012525156012619E072-9910
chr5156012723156012818E072-9711
chr5156013695156013862E072-8667
chr5156014194156014267E072-8262
chr5156015144156015335E072-7194
chr5156015383156016032E072-6497
chr5156016149156016435E072-6094
chr5156016439156016881E072-5648
chr5156018022156018965E072-3564
chr5156026001156026271E0723472
chr5156050488156050627E07227959
chr5156050775156050832E07228246
chr5155984141155984446E073-38083
chr5156011319156011639E073-10890
chr5156011651156012061E073-10468
chr5156012073156012199E073-10330
chr5156012525156012619E073-9910
chr5156012723156012818E073-9711
chr5156014194156014267E073-8262
chr5156016439156016881E073-5648
chr5156018022156018965E073-3564
chr5155984141155984446E074-38083
chr5155998621155998673E074-23856
chr5156009212156009407E074-13122
chr5156009518156009583E074-12946
chr5156011319156011639E074-10890
chr5156011651156012061E074-10468
chr5156012073156012199E074-10330
chr5156012525156012619E074-9910
chr5156012723156012818E074-9711
chr5156013695156013862E074-8667
chr5156014194156014267E074-8262
chr5156015144156015335E074-7194
chr5156015383156016032E074-6497
chr5156016149156016435E074-6094
chr5156016439156016881E074-5648
chr5156018022156018965E074-3564
chr5156019686156019744E074-2785
chr5156022296156022376E074-153
chr5156022452156022824E0740
chr5156022977156023092E074448
chr5156050488156050627E07427959
chr5156050775156050832E07428246
chr5156014194156014267E081-8262
chr5155984141155984446E082-38083