rs10517232

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0226 (6784/29910,GnomAD)
C=0225 (6575/29118,TOPMED)
C=0224 (1122/5008,1000G)
C=0225 (867/3854,ALSPAC)
C=0226 (837/3708,TWINSUK)
chr4:31934124 (GRCh38.p7) (4p15.1)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.31934124T>C
GRCh37.p13 chr 4NC_000004.11:g.31935746T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.787C=0.213
1000GenomesAmericanSub694T=0.760C=0.240
1000GenomesEast AsianSub1008T=0.725C=0.275
1000GenomesEuropeSub1006T=0.778C=0.222
1000GenomesGlobalStudy-wide5008T=0.776C=0.224
1000GenomesSouth AsianSub978T=0.830C=0.170
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.775C=0.225
The Genome Aggregation DatabaseAfricanSub8702T=0.782C=0.218
The Genome Aggregation DatabaseAmericanSub834T=0.730C=0.270
The Genome Aggregation DatabaseEast AsianSub1608T=0.688C=0.312
The Genome Aggregation DatabaseEuropeSub18464T=0.780C=0.219
The Genome Aggregation DatabaseGlobalStudy-wide29910T=0.773C=0.226
The Genome Aggregation DatabaseOtherSub302T=0.640C=0.360
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.774C=0.225
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.774C=0.226
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs105172320.000988alcohol dependence20201924

eQTL of rs10517232 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10517232 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.