rs10519442

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0123 (3695/29948,GnomAD)
G=0168 (4892/29118,TOPMED)
G=0133 (666/5008,1000G)
G=0069 (264/3854,ALSPAC)
G=0067 (250/3708,TWINSUK)
chr15:23663540 (GRCh38.p7) (15q11.2)
AD
GWASdb2
1   publication(s)
See rs on genome
10 Enhancers around
73 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 15NC_000015.10:g.23663540A>G
GRCh37.p13 chr 15NC_000015.9:g.23908687A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.686G=0.314
1000GenomesAmericanSub694A=0.930G=0.070
1000GenomesEast AsianSub1008A=0.939G=0.061
1000GenomesEuropeSub1006A=0.922G=0.078
1000GenomesGlobalStudy-wide5008A=0.867G=0.133
1000GenomesSouth AsianSub978A=0.930G=0.070
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.931G=0.069
The Genome Aggregation DatabaseAfricanSub8708A=0.719G=0.281
The Genome Aggregation DatabaseAmericanSub838A=0.920G=0.080
The Genome Aggregation DatabaseEast AsianSub1618A=0.959G=0.041
The Genome Aggregation DatabaseEuropeSub18484A=0.940G=0.059
The Genome Aggregation DatabaseGlobalStudy-wide29948A=0.876G=0.123
The Genome Aggregation DatabaseOtherSub300A=0.950G=0.050
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.832G=0.168
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.933G=0.067
PMID Title Author Journal
23953852Genome-wide association studies of maximum number of drinks.Pan YJ Psychiatr Res

P-Value

SNP ID p-value Traits Study
rs105194427.9E-05alcohol consumption23953852

eQTL of rs10519442 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10519442 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr152388742823888147E067-20540
chr152388827423888388E067-20299
chr152389399123894041E069-14646
chr152393525723936163E06926570
chr152388827423888388E071-20299
chr152393525723936163E07126570
chr152388742823888147E081-20540
chr152388827423888388E081-20299
chr152389399123894041E081-14646
chr152393525723936163E08126570




Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr152389189423891934E067-16753
chr152389199623892283E067-16404
chr152389230223892547E067-16140
chr152389266323893696E067-14991
chr152393120823931273E06722521
chr152393129523931348E06722608
chr152393140023931528E06722713
chr152393162123931928E06722934
chr152393195123932796E06723264
chr152389230223892547E068-16140
chr152389266323893696E068-14991
chr152389370623893879E068-14808
chr152393120823931273E06822521
chr152393129523931348E06822608
chr152393140023931528E06822713
chr152393162123931928E06822934
chr152393195123932796E06823264
chr152389199623892283E069-16404
chr152389230223892547E069-16140
chr152389266323893696E069-14991
chr152389370623893879E069-14808
chr152393120823931273E06922521
chr152393129523931348E06922608
chr152393140023931528E06922713
chr152393162123931928E06922934
chr152393195123932796E06923264
chr152389266323893696E070-14991
chr152389370623893879E070-14808
chr152393120823931273E07022521
chr152393129523931348E07022608
chr152393140023931528E07022713
chr152393162123931928E07022934
chr152393195123932796E07023264
chr152389230223892547E071-16140
chr152389266323893696E071-14991
chr152393120823931273E07122521
chr152393129523931348E07122608
chr152393140023931528E07122713
chr152393162123931928E07122934
chr152393195123932796E07123264
chr152389189423891934E072-16753
chr152389199623892283E072-16404
chr152389230223892547E072-16140
chr152389266323893696E072-14991
chr152393120823931273E07222521
chr152393129523931348E07222608
chr152393140023931528E07222713
chr152393162123931928E07222934
chr152393195123932796E07223264
chr152389189423891934E073-16753
chr152389199623892283E073-16404
chr152389230223892547E073-16140
chr152389266323893696E073-14991
chr152393120823931273E07322521
chr152393129523931348E07322608
chr152393140023931528E07322713
chr152393162123931928E07322934
chr152393195123932796E07323264
chr152389266323893696E074-14991
chr152393140023931528E07422713
chr152393162123931928E07422934
chr152393195123932796E07423264
chr152389266323893696E081-14991
chr152389370623893879E081-14808
chr152393120823931273E08122521
chr152393129523931348E08122608
chr152389266323893696E082-14991
chr152389370623893879E082-14808
chr152393120823931273E08222521
chr152393129523931348E08222608
chr152393140023931528E08222713
chr152393162123931928E08222934
chr152393195123932796E08223264