rs10567

Homo sapiens
C>T
DCLRE1A : 3 Prime UTR Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0013 (406/29984,GnomAD)
T=0017 (501/29118,TOPMED)
T=0009 (44/5008,1000G)
chr10:113834966 (GRCh38.p7) (10q25.3)
ND
GWASdb2
1   publication(s)
See rs on genome
76 Enhancers around
20 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.113834966C>T
GRCh37.p13 chr 10NC_000010.10:g.115594725C>T

Gene: DCLRE1A, DNA cross-link repair 1A(minus strand)

Molecule type Change Amino acid[Codon] SO Term
DCLRE1A transcript variant 2NM_014881.4:c.N/A3 Prime UTR Variant
DCLRE1A transcript variant 1NM_001271816.1:c.N/A3 Prime UTR Variant
DCLRE1A transcript variant X1XM_006718090.1:c.N/A3 Prime UTR Variant
DCLRE1A transcript variant X2XM_011540429.1:c.N/A3 Prime UTR Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.999T=0.001
1000GenomesAmericanSub694C=0.970T=0.030
1000GenomesEast AsianSub1008C=1.000T=0.000
1000GenomesEuropeSub1006C=0.979T=0.021
1000GenomesGlobalStudy-wide5008C=0.991T=0.009
1000GenomesSouth AsianSub978C=1.000T=0.000
The Genome Aggregation DatabaseAfricanSub8720C=0.995T=0.005
The Genome Aggregation DatabaseAmericanSub838C=0.980T=0.020
The Genome Aggregation DatabaseEast AsianSub1622C=0.999T=0.001
The Genome Aggregation DatabaseEuropeSub18502C=0.981T=0.018
The Genome Aggregation DatabaseGlobalStudy-wide29984C=0.986T=0.013
The Genome Aggregation DatabaseOtherSub302C=0.990T=0.010
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.982T=0.017
PMID Title Author Journal
20158304A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.Lind PATwin Res Hum Genet

P-Value

SNP ID p-value Traits Study
rs105671.12E-05alcohol and nictotine co-dependence20158304

eQTL of rs10567 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10567 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr10115616583115616710E06721858
chr10115616965115617025E06722240
chr10115617053115617125E06722328
chr10115617695115617760E06722970
chr10115618323115618397E06723598
chr10115618444115618583E06723719
chr10115619642115619704E06724917
chr10115626693115626782E06731968
chr10115626811115626905E06732086
chr10115548336115549018E068-45707
chr10115612176115612297E06817451
chr10115612539115612779E06817814
chr10115617695115617760E06822970
chr10115626693115626782E06831968
chr10115626811115626905E06832086
chr10115612176115612297E06917451
chr10115612539115612779E06917814
chr10115616583115616710E06921858
chr10115616965115617025E06922240
chr10115617053115617125E06922328
chr10115617695115617760E06922970
chr10115608960115609015E07014235
chr10115609052115609213E07014327
chr10115609234115609288E07014509
chr10115609588115609748E07014863
chr10115609908115609998E07015183
chr10115610051115610143E07015326
chr10115610283115610373E07015558
chr10115610672115610731E07015947
chr10115611250115611290E07016525
chr10115611347115611567E07016622
chr10115611621115611673E07016896
chr10115611774115611824E07017049
chr10115626693115626782E07031968
chr10115548159115548209E071-46516
chr10115548336115549018E071-45707
chr10115616583115616710E07121858
chr10115616965115617025E07122240
chr10115617053115617125E07122328
chr10115617695115617760E07122970
chr10115638568115638670E07143843
chr10115638788115638838E07144063
chr10115639052115639217E07144327
chr10115639536115639834E07144811
chr10115548159115548209E072-46516
chr10115548336115549018E072-45707
chr10115612539115612779E07217814
chr10115616583115616710E07221858
chr10115625569115625658E07230844
chr10115625693115625776E07230968
chr10115625783115625937E07231058
chr10115626693115626782E07231968
chr10115635046115635096E07240321
chr10115612176115612297E07317451
chr10115612539115612779E07317814
chr10115626693115626782E07331968
chr10115548336115549018E074-45707
chr10115612539115612779E07417814
chr10115616583115616710E07421858
chr10115639536115639834E07444811
chr10115611347115611567E08116622
chr10115611621115611673E08116896
chr10115611774115611824E08117049
chr10115612176115612297E08117451
chr10115612539115612779E08117814
chr10115616583115616710E08121858
chr10115616965115617025E08122240
chr10115617053115617125E08122328
chr10115617695115617760E08122970
chr10115618444115618583E08123719
chr10115610051115610143E08215326
chr10115610283115610373E08215558
chr10115612176115612297E08217451
chr10115612539115612779E08217814
chr10115626693115626782E08231968
chr10115626811115626905E08232086










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr10115613087115615431E06718362
chr10115615452115615541E06720727
chr10115613087115615431E06818362
chr10115615452115615541E06820727
chr10115613087115615431E06918362
chr10115615452115615541E06920727
chr10115613087115615431E07018362
chr10115615452115615541E07020727
chr10115613087115615431E07118362
chr10115615452115615541E07120727
chr10115613087115615431E07218362
chr10115615452115615541E07220727
chr10115613087115615431E07318362
chr10115615452115615541E07320727
chr10115613087115615431E07418362
chr10115615452115615541E07420727
chr10115613087115615431E08118362
chr10115615452115615541E08120727
chr10115613087115615431E08218362
chr10115615452115615541E08220727