SNP Detail Info-rs1057302

Sequence Name	Change(s)
GRCh38.p7 chr 1	NC_000001.11:g.175157287A>G
GRCh37.p13 chr 1	NC_000001.10:g.175126423A>G

Molecule type	Change	Amino acid[Codon]	SO Term
KIAA0040 transcript variant 2	NM_014656.2:c.	N/A	3 Prime UTR Variant
KIAA0040 transcript variant 1	NM_001162893.1:c.	N/A	3 Prime UTR Variant
KIAA0040 transcript variant 3	NM_001162894.1:c.	N/A	3 Prime UTR Variant
KIAA0040 transcript variant 4	NM_001162895.1:c.	N/A	3 Prime UTR Variant
KIAA0040 transcript variant 6	NM_001319231.1:c.	N/A	3 Prime UTR Variant
KIAA0040 transcript variant 5	NM_001319230.1:c.	N/A	3 Prime UTR Variant
KIAA0040 transcript variant X1	XM_017002909.1:c.	N/A	3 Prime UTR Variant
KIAA0040 transcript variant X2	XM_017002910.1:c.	N/A	3 Prime UTR Variant
KIAA0040 transcript variant X3	XM_017002911.1:c.	N/A	3 Prime UTR Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.746	G=0.254
1000Genomes	American	Sub	694	A=0.700	G=0.300
1000Genomes	East Asian	Sub	1008	A=0.899	G=0.101
1000Genomes	Europe	Sub	1006	A=0.554	G=0.446
1000Genomes	Global	Study-wide	5008	A=0.731	G=0.269
1000Genomes	South Asian	Sub	978	A=0.740	G=0.260
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.537	G=0.463
The Genome Aggregation Database	African	Sub	8700	A=0.718	G=0.282
The Genome Aggregation Database	American	Sub	834	A=0.740	G=0.260
The Genome Aggregation Database	East Asian	Sub	1618	A=0.891	G=0.109
The Genome Aggregation Database	Europe	Sub	18474	A=0.526	G=0.473
The Genome Aggregation Database	Global	Study-wide	29926	A=0.609	G=0.390
The Genome Aggregation Database	Other	Sub	300	A=0.700	G=0.300
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.660	G=0.339
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.515	G=0.485

PMID	Title	Author	Journal
21703634	A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence.	Wang KS	J Psychiatr Res
23365539	Large scale association analysis for drug addiction: results from SNP to gene.	Guo X	ScientificWorldJournal
20202923	A genome-wide association study of alcohol dependence.	Bierut LJ	Proc Natl Acad Sci U S A
21956439	Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q.	Zuo L	Neuropsychopharmacology

SNP ID	p-value	Traits	Study
rs1057302	0.000000512	alcohol dependence	21703634
rs1057302	0.00000194	alcohol dependence	20202923
rs1057302	0.00062	alcohol dependence	21956439

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr1	175127262	175127638	E067	839
chr1	175127726	175127793	E067	1303
chr1	175121212	175121706	E069	-4717
chr1	175138495	175138718	E069	12072
chr1	175117508	175117593	E070	-8830
chr1	175131566	175131616	E070	5143
chr1	175131702	175131793	E070	5279
chr1	175131845	175132044	E070	5422
chr1	175132208	175132358	E070	5785
chr1	175169465	175169525	E071	43042
chr1	175169774	175170871	E071	43351
chr1	175121212	175121706	E072	-4717
chr1	175173548	175173704	E073	47125
chr1	175173714	175173889	E073	47291
chr1	175115170	175115364	E081	-11059
chr1	175115429	175115500	E081	-10923
chr1	175115737	175116333	E081	-10090
chr1	175116438	175116534	E081	-9889
chr1	175116763	175117071	E081	-9352
chr1	175117325	175117401	E081	-9022
chr1	175117508	175117593	E081	-8830
chr1	175120951	175121040	E081	-5383
chr1	175121212	175121706	E081	-4717
chr1	175127262	175127638	E082	839
chr1	175127726	175127793	E082	1303
chr1	175173548	175173704	E082	47125
chr1	175173714	175173889	E082	47291

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr1	175160861	175163201	E067	34438
chr1	175160861	175163201	E068	34438
chr1	175160861	175163201	E069	34438
chr1	175160861	175163201	E071	34438
chr1	175160861	175163201	E072	34438
chr1	175160861	175163201	E073	34438
chr1	175160861	175163201	E074	34438
chr1	175160861	175163201	E082	34438

rs1057302