rs10739616

Homo sapiens
A>G
OR1B1 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A==0176 (5288/29910,GnomAD)
A==0205 (5993/29118,TOPMED)
A==0193 (965/5008,1000G)
A==0123 (474/3854,ALSPAC)
A==0123 (456/3708,TWINSUK)
chr9:122622509 (GRCh38.p7) (9q33.2)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
3 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 9NC_000009.12:g.122622509A>G
GRCh37.p13 chr 9NC_000009.11:g.125384788A>G

Gene: OR1B1, olfactory receptor family 1 subfamily B member 1 (gene/pseudogene)(minus strand)

Molecule type Change Amino acid[Codon] SO Term
OR1B1 transcriptNM_001004450.1:c.N/AGenic Downstream Transcript Variant
OR1B1 transcript variant X1XM_017014695.1:c.N/AGenic Downstream Transcript Variant
OR1B1 transcript variant X2XM_017014696.1:c.N/AGenic Downstream Transcript Variant
OR1B1 transcript variant X3XR_001746288.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.338G=0.662
1000GenomesAmericanSub694A=0.100G=0.900
1000GenomesEast AsianSub1008A=0.081G=0.919
1000GenomesEuropeSub1006A=0.156G=0.844
1000GenomesGlobalStudy-wide5008A=0.193G=0.807
1000GenomesSouth AsianSub978A=0.210G=0.790
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.123G=0.877
The Genome Aggregation DatabaseAfricanSub8708A=0.291G=0.709
The Genome Aggregation DatabaseAmericanSub836A=0.080G=0.920
The Genome Aggregation DatabaseEast AsianSub1614A=0.073G=0.927
The Genome Aggregation DatabaseEuropeSub18450A=0.137G=0.863
The Genome Aggregation DatabaseGlobalStudy-wide29910A=0.176G=0.823
The Genome Aggregation DatabaseOtherSub302A=0.110G=0.890
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.205G=0.794
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.123G=0.877
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs107396160.000219alcohol dependence20201924

eQTL of rs10739616 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10739616 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr9125424152125424202E07439364
chr9125424277125424445E07439489
chr9125424514125424578E07439726