SNP Detail Info-rs10743428

Organism: Homo sapiens

Alleles: T>C

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

C=0359 (10740/29902,GnomAD)
C=0313 (9129/29116,TOPMED)
C=0287 (1435/5008,1000G)
C=0480 (1848/3854,ALSPAC)
C=0480 (1779/3708,TWINSUK)

Position: chr12:21952634 (GRCh38.p7) (12p12.1)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 9 Enhancers around

Promoter: 18 Promoters around

Sequence Name	Change(s)
GRCh38.p7 chr 12	NC_000012.12:g.21952634T>C
GRCh37.p13 chr 12	NC_000012.11:g.22105568T>C

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	T=0.906	C=0.094
1000Genomes	American	Sub	694	T=0.680	C=0.320
1000Genomes	East Asian	Sub	1008	T=0.715	C=0.285
1000Genomes	Europe	Sub	1006	T=0.488	C=0.512
1000Genomes	Global	Study-wide	5008	T=0.713	C=0.287
1000Genomes	South Asian	Sub	978	T=0.710	C=0.290
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	T=0.520	C=0.480
The Genome Aggregation Database	African	Sub	8716	T=0.847	C=0.153
The Genome Aggregation Database	American	Sub	834	T=0.690	C=0.310
The Genome Aggregation Database	East Asian	Sub	1616	T=0.723	C=0.277
The Genome Aggregation Database	Europe	Sub	18434	T=0.536	C=0.463
The Genome Aggregation Database	Global	Study-wide	29902	T=0.640	C=0.359
The Genome Aggregation Database	Other	Sub	302	T=0.490	C=0.510
Trans-Omics for Precision Medicine	Global	Study-wide	29116	T=0.686	C=0.313
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	T=0.520	C=0.480

PMID	Title	Author	Journal
21314694	Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.	Kendler KS	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs10743428	0.000472	alcohol dependence	21314694

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr12	22061276	22061342	E070	-44226
chr12	22061425	22061503	E070	-44065
chr12	22061525	22061624	E070	-43944
chr12	22061973	22062013	E070	-43555
chr12	22064572	22064693	E070	-40875
chr12	22064730	22064780	E070	-40788
chr12	22064844	22064923	E070	-40645
chr12	22064929	22065085	E070	-40483
chr12	22068519	22068713	E070	-36855

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr12	22093484	22095486	E067	-10082
chr12	22092449	22092673	E068	-12895
chr12	22092819	22093189	E068	-12379
chr12	22093204	22093350	E068	-12218
chr12	22093484	22095486	E068	-10082
chr12	22093484	22095486	E069	-10082
chr12	22092449	22092673	E071	-12895
chr12	22092819	22093189	E071	-12379
chr12	22093204	22093350	E071	-12218
chr12	22093484	22095486	E071	-10082
chr12	22092449	22092673	E072	-12895
chr12	22092819	22093189	E072	-12379
chr12	22093204	22093350	E072	-12218
chr12	22093484	22095486	E072	-10082
chr12	22093204	22093350	E073	-12218
chr12	22093484	22095486	E073	-10082
chr12	22093484	22095486	E074	-10082
chr12	22093484	22095486	E082	-10082

rs10743428