SNP Detail Info-rs10762705

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

C10orf11 : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G==0450 (13466/29926,GnomAD)
G==0383 (11178/29118,TOPMED)
G==0389 (1950/5008,1000G)
A=0457 (1762/3854,ALSPAC)
A=0459 (1701/3708,TWINSUK)

Position: chr10:76268705 (GRCh38.p7) (10q22.3)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 16 Enhancers around

Promoter: 0 Promoter around

Molecule type	Change	Amino acid[Codon]	SO Term
LRMDA transcript variant 1	NM_001305581.1:c.	N/A	Intron Variant
LRMDA transcript variant 2	NM_032024.4:c.	N/A	Intron Variant
LRMDA transcript variant 3	NR_131178.1:n.	N/A	Intron Variant
C10orf11 transcript variant X3	XM_011540256.2:c.	N/A	Intron Variant
C10orf11 transcript variant X6	XM_011540257.2:c.	N/A	Intron Variant
C10orf11 transcript variant X1	XM_017016759.1:c.	N/A	Intron Variant
C10orf11 transcript variant X2	XM_017016760.1:c.	N/A	Intron Variant
C10orf11 transcript variant X5	XM_017016761.1:c.	N/A	Intron Variant
C10orf11 transcript variant X7	XM_017016762.1:c.	N/A	Genic Upstream Transcript Variant
C10orf11 transcript variant X4	XR_945833.2:n.	N/A	Intron Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.211	A=0.789
1000Genomes	American	Sub	694	G=0.440	A=0.560
1000Genomes	East Asian	Sub	1008	G=0.438	A=0.562
1000Genomes	Europe	Sub	1006	G=0.515	A=0.485
1000Genomes	Global	Study-wide	5008	G=0.389	A=0.611
1000Genomes	South Asian	Sub	978	G=0.420	A=0.580
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.543	A=0.457
The Genome Aggregation Database	African	Sub	8712	G=0.255	A=0.745
The Genome Aggregation Database	American	Sub	838	G=0.500	A=0.500
The Genome Aggregation Database	East Asian	Sub	1612	G=0.424	A=0.576
The Genome Aggregation Database	Europe	Sub	18462	G=0.541	A=0.458
The Genome Aggregation Database	Global	Study-wide	29926	G=0.450	A=0.550
The Genome Aggregation Database	Other	Sub	302	G=0.490	A=0.510
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.383	A=0.616
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.541	A=0.459

PMID	Title	Author	Journal
23089632	A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53.	Wang JC	Mol Psychiatry

SNP ID	p-value	Traits	Study
rs10762705	1.3483E-05	alcohol dependence	23089632

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr10	78062183	78062314	E068	33720
chr10	78062624	78064093	E068	34161
chr10	77990795	77990910	E070	-37553
chr10	77990975	77991684	E070	-36779
chr10	78061687	78062148	E071	33224
chr10	78062183	78062314	E071	33720
chr10	78062395	78062589	E071	33932
chr10	78062624	78064093	E071	34161
chr10	77990795	77990910	E073	-37553
chr10	78003967	78004857	E073	-23606
chr10	78004952	78005099	E073	-23364
chr10	78062183	78062314	E074	33720
chr10	78062395	78062589	E074	33932
chr10	78062624	78064093	E074	34161
chr10	78068429	78068504	E082	39966
chr10	78069326	78069425	E082	40863

rs10762705