rs10762705

Homo sapiens
G>A
C10orf11 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
G==0450 (13466/29926,GnomAD)
G==0383 (11178/29118,TOPMED)
G==0389 (1950/5008,1000G)
A=0457 (1762/3854,ALSPAC)
A=0459 (1701/3708,TWINSUK)
chr10:76268705 (GRCh38.p7) (10q22.3)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.76268705G>A
GRCh37.p13 chr 10NC_000010.10:g.78028463G>A
LRMDA RefSeqGeneNG_042180.1:g.842060G>A

Gene: C10orf11, chromosome 10 open reading frame 11(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LRMDA transcript variant 1NM_001305581.1:c.N/AIntron Variant
LRMDA transcript variant 2NM_032024.4:c.N/AIntron Variant
LRMDA transcript variant 3NR_131178.1:n.N/AIntron Variant
C10orf11 transcript variant X3XM_011540256.2:c.N/AIntron Variant
C10orf11 transcript variant X6XM_011540257.2:c.N/AIntron Variant
C10orf11 transcript variant X1XM_017016759.1:c.N/AIntron Variant
C10orf11 transcript variant X2XM_017016760.1:c.N/AIntron Variant
C10orf11 transcript variant X5XM_017016761.1:c.N/AIntron Variant
C10orf11 transcript variant X7XM_017016762.1:c.N/AGenic Upstream Transcript Variant
C10orf11 transcript variant X4XR_945833.2:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.211A=0.789
1000GenomesAmericanSub694G=0.440A=0.560
1000GenomesEast AsianSub1008G=0.438A=0.562
1000GenomesEuropeSub1006G=0.515A=0.485
1000GenomesGlobalStudy-wide5008G=0.389A=0.611
1000GenomesSouth AsianSub978G=0.420A=0.580
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.543A=0.457
The Genome Aggregation DatabaseAfricanSub8712G=0.255A=0.745
The Genome Aggregation DatabaseAmericanSub838G=0.500A=0.500
The Genome Aggregation DatabaseEast AsianSub1612G=0.424A=0.576
The Genome Aggregation DatabaseEuropeSub18462G=0.541A=0.458
The Genome Aggregation DatabaseGlobalStudy-wide29926G=0.450A=0.550
The Genome Aggregation DatabaseOtherSub302G=0.490A=0.510
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.383A=0.616
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.541A=0.459
PMID Title Author Journal
23089632A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53.Wang JCMol Psychiatry

P-Value

SNP ID p-value Traits Study
rs107627051.3483E-05alcohol dependence23089632

eQTL of rs10762705 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10762705 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr107806218378062314E06833720
chr107806262478064093E06834161
chr107799079577990910E070-37553
chr107799097577991684E070-36779
chr107806168778062148E07133224
chr107806218378062314E07133720
chr107806239578062589E07133932
chr107806262478064093E07134161
chr107799079577990910E073-37553
chr107800396778004857E073-23606
chr107800495278005099E073-23364
chr107806218378062314E07433720
chr107806239578062589E07433932
chr107806262478064093E07434161
chr107806842978068504E08239966
chr107806932678069425E08240863