rs10764581

Homo sapiens
T>A / T>C
LINC00836 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0237 (7107/29922,GnomAD)
C=0232 (6764/29118,TOPMED)
C=0206 (1031/5008,1000G)
C=0219 (844/3854,ALSPAC)
C=0215 (798/3708,TWINSUK)
chr10:25707172 (GRCh38.p7) (10p12.1)
AD
GWASdb2
1   publication(s)
See rs on genome
26 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.25707172T>A
GRCh38.p7 chr 10NC_000010.11:g.25707172T>C
GRCh37.p13 chr 10NC_000010.10:g.25996101T>A
GRCh37.p13 chr 10NC_000010.10:g.25996101T>C

Gene: LINC00836, long intergenic non-protein coding RNA 836(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LINC00836 transcript variant 1NR_108067.1:n.N/AIntron Variant
LINC00836 transcript variant 2NR_108068.1:n.N/AIntron Variant
LINC00836 transcript variant 3NR_108069.1:n.N/AGenic Downstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.721C=0.279
1000GenomesAmericanSub694T=0.830C=0.170
1000GenomesEast AsianSub1008T=0.812C=0.188
1000GenomesEuropeSub1006T=0.779C=0.221
1000GenomesGlobalStudy-wide5008T=0.794C=0.206
1000GenomesSouth AsianSub978T=0.870C=0.130
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.781C=0.219
The Genome Aggregation DatabaseAfricanSub8710T=0.732C=0.268
The Genome Aggregation DatabaseAmericanSub836T=0.810C=0.190
The Genome Aggregation DatabaseEast AsianSub1614T=0.785C=0.215
The Genome Aggregation DatabaseEuropeSub18460T=0.773C=0.226
The Genome Aggregation DatabaseGlobalStudy-wide29922T=0.762C=0.237
The Genome Aggregation DatabaseOtherSub302T=0.730C=0.270
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.767C=0.232
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.785C=0.215
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs107645810.00065alcohol dependence20201924

eQTL of rs10764581 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10764581 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr10110725687110726524E070-21546
chr10110749512110749616E0701442
chr10110749874110749986E0701804
chr10110750056110750190E0701986
chr10110750228110750577E0702158
chr10110725499110725571E081-22499
chr10110725687110726524E081-21546
chr10110726554110726604E081-21466
chr10110726679110726854E081-21216
chr10110748485110748700E081415
chr10110748860110748910E081790
chr10110749343110749393E0811273
chr10110749512110749616E0811442
chr10110749874110749986E0811804
chr10110750056110750190E0811986
chr10110750228110750577E0812158
chr10110789887110789931E08141817
chr10110790873110790978E08142803
chr10110791052110791141E08142982
chr10110725499110725571E082-22499
chr10110725687110726524E082-21546
chr10110728388110728505E082-19565
chr10110749512110749616E0821442
chr10110749874110749986E0821804
chr10110750056110750190E0821986
chr10110750228110750577E0822158