rs10766825

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0183 (5484/29958,GnomAD)
C=0183 (5335/29118,TOPMED)
C=0209 (1048/5008,1000G)
C=0172 (664/3854,ALSPAC)
C=0168 (624/3708,TWINSUK)
chr11:3244903 (GRCh38.p7) (11p15.4)
AD
GWASdb2
1   publication(s)
See rs on genome
7 Enhancers around
1 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.3244903T>C
GRCh37.p13 chr 11NC_000011.9:g.3266133T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.865C=0.135
1000GenomesAmericanSub694T=0.680C=0.320
1000GenomesEast AsianSub1008T=0.816C=0.184
1000GenomesEuropeSub1006T=0.830C=0.170
1000GenomesGlobalStudy-wide5008T=0.791C=0.209
1000GenomesSouth AsianSub978T=0.700C=0.300
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.828C=0.172
The Genome Aggregation DatabaseAfricanSub8724T=0.833C=0.167
The Genome Aggregation DatabaseAmericanSub834T=0.690C=0.310
The Genome Aggregation DatabaseEast AsianSub1620T=0.793C=0.207
The Genome Aggregation DatabaseEuropeSub18478T=0.818C=0.181
The Genome Aggregation DatabaseGlobalStudy-wide29958T=0.816C=0.183
The Genome Aggregation DatabaseOtherSub302T=0.750C=0.250
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.816C=0.183
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.832C=0.168
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs107668250.00099alcohol dependence21314694

eQTL of rs10766825 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10766825 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr1132382933238905E069-27228
chr1132526893253309E069-12824
chr1132526893253309E072-12824
chr1132534183253509E072-12624
chr1132535473253926E072-12207
chr1132379713238057E081-28076
chr1132381103238160E081-27973



Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr1132245463224813E070-41320