rs10767583

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0391 (11650/29762,GnomAD)
T=0369 (10754/29118,TOPMED)
T=0429 (2147/5008,1000G)
T=0372 (1432/3854,ALSPAC)
T=0369 (1370/3708,TWINSUK)
chr11:26805163 (GRCh38.p7) (11p14.2)
AD
GWASdb2
1   publication(s)
See rs on genome
22 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.26805163C>T
GRCh37.p13 chr 11NC_000011.9:g.26826710C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.651T=0.349
1000GenomesAmericanSub694C=0.530T=0.470
1000GenomesEast AsianSub1008C=0.509T=0.491
1000GenomesEuropeSub1006C=0.600T=0.400
1000GenomesGlobalStudy-wide5008C=0.571T=0.429
1000GenomesSouth AsianSub978C=0.530T=0.470
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.628T=0.372
The Genome Aggregation DatabaseAfricanSub8682C=0.657T=0.343
The Genome Aggregation DatabaseAmericanSub830C=0.440T=0.560
The Genome Aggregation DatabaseEast AsianSub1532C=0.467T=0.533
The Genome Aggregation DatabaseEuropeSub18416C=0.606T=0.394
The Genome Aggregation DatabaseGlobalStudy-wide29762C=0.608T=0.391
The Genome Aggregation DatabaseOtherSub302C=0.540T=0.460
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.630T=0.369
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.631T=0.369
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs107675837.4E-05alcohol dependence24277619

eQTL of rs10767583 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10767583 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr112677747126777592E072-49118
chr112678863826788917E074-37793
chr112687024526870452E07443535
chr112687051726870610E07443807
chr112685517626855264E08128466
chr112685527426855325E08128564
chr112685545926855743E08128749
chr112685779226858116E08131082
chr112687051726870610E08143807
chr112687062526870880E08143915
chr112687091026871156E08144200
chr112687159826872082E08144888
chr112687217226872330E08145462
chr112687254626872734E08145836
chr112687279326872867E08146083
chr112687297126873107E08146261
chr112687319626873948E08146486
chr112687438026874521E08147670
chr112687473026874856E08148020
chr112687492226874972E08148212
chr112687505926875195E08148349
chr112687217226872330E08245462