rs10768556

Homo sapiens
C>A
LOC105376637 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C==0136 (4087/29942,GnomAD)
C==0189 (5513/29118,TOPMED)
C==0183 (914/5008,1000G)
C==0044 (170/3854,ALSPAC)
C==0043 (159/3708,TWINSUK)
chr11:39880893 (GRCh38.p7) (11p12)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.39880893C>A
GRCh37.p13 chr 11NC_000011.9:g.39902443C>A

Gene: LOC105376637, uncharacterized LOC105376637(minus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC105376637 transcript variant X1XR_001748194.1:n.N/AIntron Variant
LOC105376637 transcript variant X2XR_001748195.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.441A=0.559
1000GenomesAmericanSub694C=0.050A=0.950
1000GenomesEast AsianSub1008C=0.149A=0.851
1000GenomesEuropeSub1006C=0.037A=0.963
1000GenomesGlobalStudy-wide5008C=0.183A=0.817
1000GenomesSouth AsianSub978C=0.110A=0.890
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.044A=0.956
The Genome Aggregation DatabaseAfricanSub8692C=0.367A=0.633
The Genome Aggregation DatabaseAmericanSub838C=0.050A=0.950
The Genome Aggregation DatabaseEast AsianSub1614C=0.159A=0.841
The Genome Aggregation DatabaseEuropeSub18496C=0.031A=0.968
The Genome Aggregation DatabaseGlobalStudy-wide29942C=0.136A=0.863
The Genome Aggregation DatabaseOtherSub302C=0.040A=0.960
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.189A=0.810
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.043A=0.957
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs107685560.0004alcohol dependence20201924

eQTL of rs10768556 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10768556 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.