rs10768576

Homo sapiens
G>A / G>C
None
Check p-value
SNV (Single Nucleotide Variation)
G==0204 (6114/29900,GnomAD)
G==0189 (5513/29118,TOPMED)
G==0255 (1276/5008,1000G)
G==0160 (617/3854,ALSPAC)
G==0146 (540/3708,TWINSUK)
chr11:40052270 (GRCh38.p7) (11p12)
AD
GWASdb2
1   publication(s)
See rs on genome
182 Enhancers around
55 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.40052270G>A
GRCh38.p7 chr 11NC_000011.10:g.40052270G>C
GRCh37.p13 chr 11NC_000011.9:g.40073820G>A
GRCh37.p13 chr 11NC_000011.9:g.40073820G>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.272A=0.728
1000GenomesAmericanSub694G=0.250A=0.750
1000GenomesEast AsianSub1008G=0.412A=0.588
1000GenomesEuropeSub1006G=0.170A=0.830
1000GenomesGlobalStudy-wide5008G=0.255A=0.745
1000GenomesSouth AsianSub978G=0.160A=0.840
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.160A=0.840
The Genome Aggregation DatabaseAfricanSub8716G=0.232C=0.000
The Genome Aggregation DatabaseAmericanSub836G=0.250C=0.00,
The Genome Aggregation DatabaseEast AsianSub1572G=0.431C=0.000
The Genome Aggregation DatabaseEuropeSub18476G=0.171C=0.000
The Genome Aggregation DatabaseGlobalStudy-wide29900G=0.204C=0.000
The Genome Aggregation DatabaseOtherSub300G=0.140C=0.00,
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.189A=0.810
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.146A=0.854
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs107685760.00055alcohol dependence20201924

eQTL of rs10768576 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10768576 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr116478289464782948E067-48172
chr116478309464783134E067-47986
chr116485282564853049E06721705
chr116485309164853224E06721971
chr116485322864853306E06722108
chr116485335064853525E06722230
chr116486475964865218E06733639
chr116486892964869193E06737809
chr116486933064869407E06738210
chr116486940864869479E06738288
chr116486948664869683E06738366
chr116486973464870280E06738614
chr116487108164871332E06739961
chr116487166864871954E06740548
chr116487225464872384E06741134
chr116487246164872604E06741341
chr116487265764872701E06741537
chr116478289464782948E068-48172
chr116480985764809953E068-21167
chr116480995864810008E068-21112
chr116485282564853049E06821705
chr116485309164853224E06821971
chr116485322864853306E06822108
chr116485335064853525E06822230
chr116485810264858142E06826982
chr116485816064858445E06827040
chr116486294764863078E06831827
chr116486873764868819E06837617
chr116486892964869193E06837809
chr116486933064869407E06838210
chr116486940864869479E06838288
chr116486948664869683E06838366
chr116486973464870280E06838614
chr116487031364870412E06839193
chr116487050464870587E06839384
chr116487108164871332E06839961
chr116487166864871954E06840548
chr116487225464872384E06841134
chr116478289464782948E069-48172
chr116478309464783134E069-47986
chr116478423964784555E069-46565
chr116480446764804632E069-26488
chr116485269064852810E06921570
chr116485282564853049E06921705
chr116485309164853224E06921971
chr116485810264858142E06926982
chr116485816064858445E06927040
chr116486591064866105E06934790
chr116486858464868673E06937464
chr116486873764868819E06937617
chr116486892964869193E06937809
chr116486933064869407E06938210
chr116486940864869479E06938288
chr116486948664869683E06938366
chr116487108164871332E06939961
chr116487166864871954E06940548
chr116487225464872384E06941134
chr116487246164872604E06941341
chr116487265764872701E06941537
chr116481130764811675E070-19445
chr116481365164813695E070-17425
chr116481370164813747E070-17373
chr116481383364813877E070-17243
chr116481402964814079E070-17041
chr116481408364814292E070-16828
chr116484973664849877E07018616
chr116485269064852810E07021570
chr116478289464782948E071-48172
chr116480446764804632E071-26488
chr116480985764809953E071-21167
chr116480995864810008E071-21112
chr116481010664810236E071-20884
chr116485269064852810E07121570
chr116485282564853049E07121705
chr116485309164853224E07121971
chr116485322864853306E07122108
chr116485335064853525E07122230
chr116485810264858142E07126982
chr116485816064858445E07127040
chr116486475964865218E07133639
chr116486525764865368E07134137
chr116486858464868673E07137464
chr116486873764868819E07137617
chr116486892964869193E07137809
chr116486933064869407E07138210
chr116486940864869479E07138288
chr116486948664869683E07138366
chr116487050464870587E07139384
chr116487108164871332E07139961
chr116487166864871954E07140548
chr116487225464872384E07141134
chr116487246164872604E07141341
chr116478413464784193E072-46927
chr116478423964784555E072-46565
chr116485269064852810E07221570
chr116485282564853049E07221705
chr116485309164853224E07221971
chr116485322864853306E07222108
chr116485335064853525E07222230
chr116486525764865368E07234137
chr116486566664865706E07234546
chr116486591064866105E07234790
chr116486657064866685E07235450
chr116486892964869193E07237809
chr116486933064869407E07238210
chr116486940864869479E07238288
chr116486948664869683E07238366
chr116487050464870587E07239384
chr116487108164871332E07239961
chr116487166864871954E07240548
chr116487225464872384E07241134
chr116487246164872604E07241341
chr116487265764872701E07241537
chr116487298964873042E07241869
chr116487313464873190E07242014
chr116478423964784555E073-46565
chr116485269064852810E07321570
chr116485282564853049E07321705
chr116485309164853224E07321971
chr116486933064869407E07338210
chr116486940864869479E07338288
chr116487031364870412E07339193
chr116487050464870587E07339384
chr116487108164871332E07339961
chr116487166864871954E07340548
chr116487225464872384E07341134
chr116487246164872604E07341341
chr116478289464782948E074-48172
chr116480446764804632E074-26488
chr116480760764807663E074-23457
chr116480774264807818E074-23302
chr116480786864807908E074-23212
chr116480792864807978E074-23142
chr116485269064852810E07421570
chr116485282564853049E07421705
chr116485309164853224E07421971
chr116485322864853306E07422108
chr116485335064853525E07422230
chr116485370064853860E07422580
chr116485391564853974E07422795
chr116485810264858142E07426982
chr116485816064858445E07427040
chr116486858464868673E07437464
chr116486873764868819E07437617
chr116486892964869193E07437809
chr116486933064869407E07438210
chr116486940864869479E07438288
chr116486948664869683E07438366
chr116486973464870280E07438614
chr116487050464870587E07439384
chr116487108164871332E07439961
chr116487166864871954E07440548
chr116487225464872384E07441134
chr116487313464873190E07442014
chr116478289464782948E081-48172
chr116478371964783773E081-47347
chr116478380564783857E081-47263
chr116478389764783974E081-47146
chr116480760764807663E081-23457
chr116480774264807818E081-23302
chr116480786864807908E081-23212
chr116480792864807978E081-23142
chr116480985764809953E081-21167
chr116480995864810008E081-21112
chr116481010664810236E081-20884
chr116481051264810683E081-20437
chr116485269064852810E08121570
chr116486591064866105E08134790
chr116478423964784555E082-46565
chr116478497064785024E082-46096
chr116478517864785237E082-45883
chr116481051264810683E082-20437
chr116481077764810859E082-20261
chr116481086164810940E082-20180
chr116481098464811061E082-20059
chr116481402964814079E082-17041
chr116481408364814292E082-16828
chr116481430164814355E082-16765
chr116481437064814420E082-16700
chr116481443664814538E082-16582
chr116485269064852810E08221570
chr116486827664868380E08237156










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr116479430064796059E067-35061
chr116480801164809541E067-21579
chr116481493464815083E067-16037
chr116481510964815512E067-15608
chr116481557164815748E067-15372
chr116485066664852468E06719546
chr116486308864864548E06731968
chr116479430064796059E068-35061
chr116480801164809541E068-21579
chr116481493464815083E068-16037
chr116481510964815512E068-15608
chr116481557164815748E068-15372
chr116485066664852468E06819546
chr116486308864864548E06831968
chr116479430064796059E069-35061
chr116480801164809541E069-21579
chr116485066664852468E06919546
chr116486308864864548E06931968
chr116479430064796059E070-35061
chr116480801164809541E070-21579
chr116481557164815748E070-15372
chr116485066664852468E07019546
chr116486308864864548E07031968
chr116479430064796059E071-35061
chr116480801164809541E071-21579
chr116481493464815083E071-16037
chr116481510964815512E071-15608
chr116481557164815748E071-15372
chr116485066664852468E07119546
chr116486308864864548E07131968
chr116479430064796059E072-35061
chr116480801164809541E072-21579
chr116481493464815083E072-16037
chr116481510964815512E072-15608
chr116485066664852468E07219546
chr116486308864864548E07231968
chr116479430064796059E073-35061
chr116480801164809541E073-21579
chr116481510964815512E073-15608
chr116481557164815748E073-15372
chr116485066664852468E07319546
chr116486308864864548E07331968
chr116479430064796059E074-35061
chr116480801164809541E074-21579
chr116485066664852468E07419546
chr116486308864864548E07431968
chr116479430064796059E081-35061
chr116486308864864548E08131968
chr116479430064796059E082-35061
chr116480801164809541E082-21579
chr116481493464815083E082-16037
chr116481510964815512E082-15608
chr116481557164815748E082-15372
chr116485066664852468E08219546
chr116486308864864548E08231968