rs10771224

Homo sapiens
T>C
LMNTD1 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0483 (14370/29726,GnomAD)
C=0474 (13819/29118,TOPMED)
T==0475 (2380/5008,1000G)
C=0415 (1600/3854,ALSPAC)
C=0412 (1528/3708,TWINSUK)
chr12:25506738 (GRCh38.p7) (12p12.1)
AD
GWASdb2
1   publication(s)
See rs on genome
5 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 12NC_000012.12:g.25506738T>C
GRCh37.p13 chr 12NC_000012.11:g.25659672T>C

Gene: LMNTD1, lamin tail domain containing 1(minus strand)

Molecule type Change Amino acid[Codon] SO Term
LMNTD1 transcript variant 3NM_001145727.2:c.N/AIntron Variant
LMNTD1 transcript variant 1NM_001145728.2:c.N/AIntron Variant
LMNTD1 transcript variant 4NM_001145729.1:c.N/AIntron Variant
LMNTD1 transcript variant 5NM_001256266.1:c.N/AIntron Variant
LMNTD1 transcript variant 2NM_152590.3:c.N/AIntron Variant
LMNTD1 transcript variant X1XM_011520575.1:c.N/AIntron Variant
LMNTD1 transcript variant X2XM_011520576.2:c.N/AIntron Variant
LMNTD1 transcript variant X3XM_011520577.2:c.N/AIntron Variant
LMNTD1 transcript variant X4XM_011520578.2:c.N/AIntron Variant
LMNTD1 transcript variant X7XM_011520580.1:c.N/AIntron Variant
LMNTD1 transcript variant X9XM_011520582.1:c.N/AIntron Variant
LMNTD1 transcript variant X8XM_011520583.1:c.N/AIntron Variant
LMNTD1 transcript variant X11XM_011520584.1:c.N/AIntron Variant
LMNTD1 transcript variant X12XM_011520585.2:c.N/AIntron Variant
LMNTD1 transcript variant X17XM_011520587.1:c.N/AIntron Variant
LMNTD1 transcript variant X15XM_011520588.1:c.N/AIntron Variant
LMNTD1 transcript variant X5XM_017018891.1:c.N/AIntron Variant
LMNTD1 transcript variant X10XM_017018892.1:c.N/AIntron Variant
LMNTD1 transcript variant X13XM_017018893.1:c.N/AIntron Variant
LMNTD1 transcript variant X6XM_011520579.2:c.N/AGenic Downstream Transcript Variant
LMNTD1 transcript variant X13XM_017018894.1:c.N/AGenic Downstream Transcript Variant
LMNTD1 transcript variant X16XM_017018895.1:c.N/AGenic Downstream Transcript Variant
LMNTD1 transcript variant X11XR_931276.1:n.N/AGenic Downstream Transcript Variant
LMNTD1 transcript variant X12XR_931277.1:n.N/AGenic Downstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.474C=0.526
1000GenomesAmericanSub694T=0.440C=0.560
1000GenomesEast AsianSub1008T=0.397C=0.603
1000GenomesEuropeSub1006T=0.555C=0.445
1000GenomesGlobalStudy-wide5008T=0.475C=0.525
1000GenomesSouth AsianSub978T=0.500C=0.500
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.585C=0.415
The Genome Aggregation DatabaseAfricanSub8610T=0.493C=0.507
The Genome Aggregation DatabaseAmericanSub834T=0.500C=0.500
The Genome Aggregation DatabaseEast AsianSub1588T=0.349C=0.651
The Genome Aggregation DatabaseEuropeSub18392T=0.540C=0.459
The Genome Aggregation DatabaseGlobalStudy-wide29726T=0.516C=0.483
The Genome Aggregation DatabaseOtherSub302T=0.670C=0.330
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.525C=0.474
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.588C=0.412
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs107712240.0005alcohol dependence21314694

eQTL of rs10771224 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10771224 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr122563563525635847E070-23825
chr122563590025635964E070-23708
chr122566026425660510E070592
chr122566051325660713E070841
chr122564798025648334E081-11338