rs1078826

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0396 (11851/29876,GnomAD)
A=0349 (10177/29118,TOPMED)
A=0421 (2108/5008,1000G)
A=0455 (1755/3854,ALSPAC)
A=0469 (1740/3708,TWINSUK)
chr2:129233439 (GRCh38.p7) (2q21.1)
AD
GWASdb2
1   publication(s)
See rs on genome
16 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.129233439G>A
GRCh37.p13 chr 2NC_000002.11:g.129991012G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.835A=0.165
1000GenomesAmericanSub694G=0.490A=0.510
1000GenomesEast AsianSub1008G=0.293A=0.707
1000GenomesEuropeSub1006G=0.572A=0.428
1000GenomesGlobalStudy-wide5008G=0.579A=0.421
1000GenomesSouth AsianSub978G=0.600A=0.400
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.545A=0.455
The Genome Aggregation DatabaseAfricanSub8704G=0.791A=0.209
The Genome Aggregation DatabaseAmericanSub836G=0.480A=0.520
The Genome Aggregation DatabaseEast AsianSub1616G=0.223A=0.777
The Genome Aggregation DatabaseEuropeSub18418G=0.553A=0.446
The Genome Aggregation DatabaseGlobalStudy-wide29876G=0.603A=0.396
The Genome Aggregation DatabaseOtherSub302G=0.620A=0.380
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.650A=0.349
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.531A=0.469
PMID Title Author Journal
24962325Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.Kapoor MDrug Alcohol Depend

P-Value

SNP ID p-value Traits Study
rs10788265.69E-06alcohol dependence (age at onset)24962325

eQTL of rs1078826 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1078826 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr2129990903129991022E0700
chr2129991443129991904E070431
chr2129990903129991022E0810
chr2129991443129991904E081431
chr2129996773129997036E0815761
chr2130010223130010353E08119211
chr2130010398130011293E08119386
chr2130038915130039052E08147903
chr2130039472130039687E08148460
chr2130039843130039996E08148831
chr2129996773129997036E0825761
chr2130010223130010353E08219211
chr2130038591130038845E08247579
chr2130038915130039052E08247903
chr2130039472130039687E08248460
chr2130039843130039996E08248831