rs10794595

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0378 (11323/29950,GnomAD)
T==0397 (11559/29118,TOPMED)
T==0303 (1518/5008,1000G)
T==0347 (1338/3854,ALSPAC)
T==0348 (1291/3708,TWINSUK)
chr10:123121986 (GRCh38.p7) (10q26.13)
ND
GWASdb2
1   publication(s)
See rs on genome
13 Enhancers around
10 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.123121986T>C
GRCh37.p13 chr 10NC_000010.10:g.124881502T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.516C=0.484
1000GenomesAmericanSub694T=0.300C=0.700
1000GenomesEast AsianSub1008T=0.124C=0.876
1000GenomesEuropeSub1006T=0.309C=0.691
1000GenomesGlobalStudy-wide5008T=0.303C=0.697
1000GenomesSouth AsianSub978T=0.200C=0.800
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.347C=0.653
The Genome Aggregation DatabaseAfricanSub8726T=0.478C=0.522
The Genome Aggregation DatabaseAmericanSub838T=0.260C=0.740
The Genome Aggregation DatabaseEast AsianSub1622T=0.113C=0.887
The Genome Aggregation DatabaseEuropeSub18462T=0.362C=0.638
The Genome Aggregation DatabaseGlobalStudy-wide29950T=0.378C=0.621
The Genome Aggregation DatabaseOtherSub302T=0.200C=0.800
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.397C=0.603
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.348C=0.652
PMID Title Author Journal
19268276Genome-wide association study of smoking initiation and current smoking.Vink JMAm J Hum Genet

P-Value

SNP ID p-value Traits Study
rs107945954.33E-06nicotine smoking19268276

eQTL of rs10794595 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10794595 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr10124878152124878215E070-3287
chr10124878266124878316E070-3186
chr10124878496124878897E070-2605
chr10124915776124915894E07034274
chr10124915937124915991E07034435
chr10124916033124916083E07034531
chr10124916129124916198E07034627
chr10124916573124916637E07035071
chr10124916697124916798E07035195
chr10124916848124917105E07035346
chr10124915776124915894E07134274
chr10124915937124915991E07134435
chr10124878152124878215E074-3287



Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr10124913006124914940E06731504
chr10124913006124914940E06831504
chr10124913006124914940E06931504
chr10124913006124914940E07031504
chr10124913006124914940E07131504
chr10124913006124914940E07231504
chr10124913006124914940E07331504
chr10124913006124914940E07431504
chr10124913006124914940E08131504
chr10124913006124914940E08231504