rs10800021

Homo sapiens
C>G
None
Check p-value
SNV (Single Nucleotide Variation)
C==0317 (9235/29118,TOPMED)
C==0342 (9820/28652,GnomAD)
C==0389 (1946/5008,1000G)
C==0376 (1451/3854,ALSPAC)
C==0369 (1367/3708,TWINSUK)
chr1:164485412 (GRCh38.p7) (1q23.3)
ND
GWASdb2
1   publication(s)
See rs on genome
33 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 1NC_000001.11:g.164485412C>G
GRCh37.p13 chr 1NC_000001.10:g.164454649C>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.221G=0.779
1000GenomesAmericanSub694C=0.440G=0.560
1000GenomesEast AsianSub1008C=0.614G=0.386
1000GenomesEuropeSub1006C=0.352G=0.648
1000GenomesGlobalStudy-wide5008C=0.389G=0.611
1000GenomesSouth AsianSub978C=0.380G=0.620
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.376G=0.624
The Genome Aggregation DatabaseAfricanSub8518C=0.225G=0.775
The Genome Aggregation DatabaseAmericanSub814C=0.480G=0.520
The Genome Aggregation DatabaseEast AsianSub1594C=0.639G=0.361
The Genome Aggregation DatabaseEuropeSub17424C=0.366G=0.633
The Genome Aggregation DatabaseGlobalStudy-wide28652C=0.342G=0.657
The Genome Aggregation DatabaseOtherSub302C=0.350G=0.650
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.317G=0.682
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.369G=0.631
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs108000210.000186nicotine dependence17158188

eQTL of rs10800021 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10800021 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr1164484533164484759E06729884
chr1164484975164485125E06730326
chr1164485293164485545E06730644
chr1164487988164488543E06733339
chr1164488836164489003E06734187
chr1164485293164485545E06830644
chr1164485708164485758E06831059
chr1164484533164484759E06929884
chr1164485293164485545E06930644
chr1164487988164488543E06933339
chr1164488836164489003E06934187
chr1164465168164465714E07010519
chr1164465758164465935E07011109
chr1164485293164485545E07030644
chr1164485708164485758E07031059
chr1164487988164488543E07033339
chr1164488836164489003E07034187
chr1164487988164488543E07133339
chr1164488836164489003E07134187
chr1164409285164409913E072-44736
chr1164484533164484759E07229884
chr1164484975164485125E07230326
chr1164485293164485545E07230644
chr1164487988164488543E07233339
chr1164488836164489003E07234187
chr1164484975164485125E07430326
chr1164485293164485545E07430644
chr1164487530164487604E07432881
chr1164487988164488543E07433339
chr1164488836164489003E07434187
chr1164487988164488543E08133339
chr1164487988164488543E08233339
chr1164488836164489003E08234187