rs10801629

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0421 (12609/29904,GnomAD)
T=0450 (13127/29118,TOPMED)
T=0428 (2141/5008,1000G)
T=0399 (1538/3854,ALSPAC)
T=0412 (1529/3708,TWINSUK)
chr1:197875237 (GRCh38.p7) (1q31.3)
AD
GWASdb2
2   publication(s)
See rs on genome
2 Enhancers around
11 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 1NC_000001.11:g.197875237C>T
GRCh37.p13 chr 1NC_000001.10:g.197844367C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.474T=0.526
1000GenomesAmericanSub694C=0.660T=0.340
1000GenomesEast AsianSub1008C=0.651T=0.349
1000GenomesEuropeSub1006C=0.581T=0.419
1000GenomesGlobalStudy-wide5008C=0.572T=0.428
1000GenomesSouth AsianSub978C=0.560T=0.440
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.601T=0.399
The Genome Aggregation DatabaseAfricanSub8690C=0.516T=0.484
The Genome Aggregation DatabaseAmericanSub836C=0.640T=0.360
The Genome Aggregation DatabaseEast AsianSub1616C=0.683T=0.317
The Genome Aggregation DatabaseEuropeSub18462C=0.596T=0.403
The Genome Aggregation DatabaseGlobalStudy-wide29904C=0.578T=0.421
The Genome Aggregation DatabaseOtherSub300C=0.550T=0.450
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.549T=0.450
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.588T=0.412
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res
23691058Dosage transmission disequilibrium test (dTDT) for linkage and association detection.Zhang ZPLoS One

P-Value

SNP ID p-value Traits Study
rs108016290.00000413alcohol dependence23691058
rs108016290.00027alcohol dependence20201924

eQTL of rs10801629 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10801629 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr1197811062197811624E081-32743
chr1197883768197883932E08139401

Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr1197871298197872621E06726931
chr1197871298197872621E06826931
chr1197884124197887887E06839757
chr1197871298197872621E06926931
chr1197871298197872621E07026931
chr1197871298197872621E07126931
chr1197871298197872621E07226931
chr1197871298197872621E07326931
chr1197871298197872621E07426931
chr1197871298197872621E08126931
chr1197871298197872621E08226931