SNP Detail Info-rs10808154

Sequence Name	Change(s)
GRCh38.p7 chr 7	NC_000007.14:g.107745951G>A
GRCh37.p13 chr 7	NC_000007.13:g.107386396G>A

Molecule type	Change	Amino acid[Codon]	SO Term
CBLL1 transcript variant 3	NM_001284291.1:c.	N/A	Intron Variant
CBLL1 transcript variant 1	NM_024814.3:c.	N/A	Intron Variant
CBLL1 transcript variant 2	NR_024199.2:n.	N/A	Intron Variant
CBLL1 transcript variant X3	XM_011516580.2:c.	N/A	Intron Variant
CBLL1 transcript variant X1	XM_017012643.1:c.	N/A	Intron Variant
CBLL1 transcript variant X6	XM_017012644.1:c.	N/A	Intron Variant
CBLL1 transcript variant X8	XM_017012645.1:c.	N/A	Intron Variant

Molecule type	Change	Amino acid[Codon]	SO Term
LOC101927974 transcript variant X1	XR_927849.2:n.	N/A	Upstream Transcript Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.983	A=0.017
1000Genomes	American	Sub	694	G=0.720	A=0.280
1000Genomes	East Asian	Sub	1008	G=0.646	A=0.354
1000Genomes	Europe	Sub	1006	G=0.736	A=0.264
1000Genomes	Global	Study-wide	5008	G=0.740	A=0.260
1000Genomes	South Asian	Sub	978	G=0.530	A=0.470
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.759	A=0.241
The Genome Aggregation Database	African	Sub	8714	G=0.947	A=0.053
The Genome Aggregation Database	American	Sub	836	G=0.690	A=0.310
The Genome Aggregation Database	East Asian	Sub	1606	G=0.625	A=0.375
The Genome Aggregation Database	Europe	Sub	18436	G=0.719	A=0.280
The Genome Aggregation Database	Global	Study-wide	29892	G=0.780	A=0.219
The Genome Aggregation Database	Other	Sub	300	G=0.780	A=0.220
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.841	A=0.159
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.748	A=0.252

PMID	Title	Author	Journal
23743675	A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.	Kapoor M	Hum Genet

SNP ID	p-value	Traits	Study
rs10808154	8.33E-05	alcohol consumption	23743675

eQTL of rs10808154 in Brain tissues (GTEx Analysis Release V7)

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
Chr7:107386396	AC002467.7	ENSG00000241764.3	G>A	1.1747e-4	1515	Cerebellum
Chr7:107386396	AC002467.7	ENSG00000241764.3	G>A	2.1985e-5	1515	Frontal_Cortex_BA9
Chr7:107386396	AC002467.7	ENSG00000241764.3	G>A	1.0521e-4	1515	Cortex
Chr7:107386396	AC002467.7	ENSG00000241764.3	G>A	4.1131e-5	1515	Cerebellar_Hemisphere
Chr7:107386396	AC002467.7	ENSG00000241764.3	G>A	4.3055e-3	1515	Caudate_basal_ganglia
Chr7:107386396	AC002467.7	ENSG00000241764.3	G>A	2.6099e-4	1515	Anterior_cingulate_cortex
Chr7:107386396	AC002467.7	ENSG00000241764.3	G>A	1.0776e-3	1515	Nucleus_accumbens_basal_ganglia

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr7	107383023	107383099	E067	-3297
chr7	107386669	107386772	E067	273
chr7	107387624	107387709	E067	1228
chr7	107387798	107387880	E067	1402
chr7	107341168	107341256	E068	-45140
chr7	107341276	107341497	E068	-44899
chr7	107382753	107382818	E068	-3578
chr7	107386669	107386772	E068	273
chr7	107387624	107387709	E068	1228
chr7	107387798	107387880	E068	1402
chr7	107387932	107387978	E068	1536
chr7	107388350	107388400	E068	1954
chr7	107337294	107337374	E069	-49022
chr7	107337495	107337545	E069	-48851
chr7	107383023	107383099	E069	-3297
chr7	107386669	107386772	E069	273
chr7	107387624	107387709	E069	1228
chr7	107387798	107387880	E069	1402
chr7	107387932	107387978	E069	1536
chr7	107337495	107337545	E070	-48851
chr7	107337639	107338679	E070	-47717
chr7	107383023	107383099	E070	-3297
chr7	107386669	107386772	E070	273
chr7	107387798	107387880	E070	1402
chr7	107387932	107387978	E070	1536
chr7	107388350	107388400	E070	1954
chr7	107337495	107337545	E071	-48851
chr7	107337639	107338679	E071	-47717
chr7	107383023	107383099	E071	-3297
chr7	107337639	107338679	E072	-47717
chr7	107383023	107383099	E072	-3297
chr7	107386669	107386772	E072	273
chr7	107337639	107338679	E073	-47717
chr7	107337639	107338679	E081	-47717
chr7	107338996	107339076	E081	-47320
chr7	107337294	107337374	E082	-49022
chr7	107337495	107337545	E082	-48851
chr7	107337639	107338679	E082	-47717
chr7	107386669	107386772	E082	273
chr7	107387798	107387880	E082	1402
chr7	107387932	107387978	E082	1536
chr7	107388350	107388400	E082	1954

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr7	107383118	107385525	E067	-871
chr7	107383118	107385525	E068	-871
chr7	107383118	107385525	E069	-871
chr7	107383118	107385525	E070	-871
chr7	107383118	107385525	E071	-871
chr7	107383118	107385525	E072	-871
chr7	107383118	107385525	E073	-871
chr7	107383118	107385525	E074	-871
chr7	107383118	107385525	E081	-871
chr7	107383118	107385525	E082	-871

rs10808154