rs10808365

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0127 (3813/29950,GnomAD)
C=0140 (4096/29118,TOPMED)
C=0175 (876/5008,1000G)
C=0060 (230/3854,ALSPAC)
C=0048 (179/3708,TWINSUK)
chr8:100798263 (GRCh38.p7) (8q22.3)
AD
GWASdb2
2   publication(s)
See rs on genome
21 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.100798263T>C
GRCh37.p13 chr 8NC_000008.10:g.101810491T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.756C=0.244
1000GenomesAmericanSub694T=0.800C=0.200
1000GenomesEast AsianSub1008T=0.711C=0.289
1000GenomesEuropeSub1006T=0.948C=0.052
1000GenomesGlobalStudy-wide5008T=0.825C=0.175
1000GenomesSouth AsianSub978T=0.930C=0.070
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.940C=0.060
The Genome Aggregation DatabaseAfricanSub8704T=0.763C=0.237
The Genome Aggregation DatabaseAmericanSub834T=0.800C=0.200
The Genome Aggregation DatabaseEast AsianSub1612T=0.687C=0.313
The Genome Aggregation DatabaseEuropeSub18498T=0.942C=0.057
The Genome Aggregation DatabaseGlobalStudy-wide29950T=0.872C=0.127
The Genome Aggregation DatabaseOtherSub302T=0.950C=0.050
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.859C=0.140
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.952C=0.048
PMID Title Author Journal
21989058Association of 8q22.3 locus in Chinese Han with idiopathic premature ovarian failure (POF).Qin YHum Mol Genet
23743675A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.Kapoor MHum Genet

P-Value

SNP ID p-value Traits Study
rs108083654.18E-05alcohol consumption23743675

eQTL of rs10808365 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10808365 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr8101773554101775046E068-35445
chr8101847470101848214E06836979
chr8101762717101763214E071-47277
chr8101764400101764498E071-45993
chr8101764560101764751E071-45740
chr8101764770101764823E071-45668
chr8101803597101803661E072-6830
chr8101803758101804338E074-6153
chr8101804391101804510E074-5981
chr8101847470101848214E07436979
chr8101848259101848339E07437768
chr8101859230101859295E07448739
chr8101775773101775823E081-34668
chr8101775832101775882E081-34609
chr8101775951101776079E081-34412
chr8101803597101803661E081-6830
chr8101803758101804338E081-6153
chr8101804391101804510E081-5981
chr8101851627101851825E08141136
chr8101851845101851917E08141354
chr8101775334101775644E082-34847