rs10808570

Homo sapiens
A>C
LINC00824 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0170 (5119/29954,GnomAD)
C=0181 (5274/29118,TOPMED)
C=0205 (1028/5008,1000G)
C=0151 (582/3854,ALSPAC)
C=0120 (446/3708,TWINSUK)
chr8:128451289 (GRCh38.p7) (8q24.21)
AD
GWASdb2
1   publication(s)
See rs on genome
6 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.128451289A>C
GRCh37.p13 chr 8NC_000008.10:g.129463535A>C

Gene: LINC00824, long intergenic non-protein coding RNA 824(minus strand)

Molecule type Change Amino acid[Codon] SO Term
LINC00824 transcript variant 1NR_121672.1:n.N/AIntron Variant
LINC00824 transcript variant 2NR_121673.1:n.N/AGenic Downstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.769C=0.231
1000GenomesAmericanSub694A=0.860C=0.140
1000GenomesEast AsianSub1008A=0.724C=0.276
1000GenomesEuropeSub1006A=0.859C=0.141
1000GenomesGlobalStudy-wide5008A=0.795C=0.205
1000GenomesSouth AsianSub978A=0.790C=0.210
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.849C=0.151
The Genome Aggregation DatabaseAfricanSub8710A=0.767C=0.233
The Genome Aggregation DatabaseAmericanSub838A=0.880C=0.120
The Genome Aggregation DatabaseEast AsianSub1616A=0.707C=0.293
The Genome Aggregation DatabaseEuropeSub18490A=0.866C=0.133
The Genome Aggregation DatabaseGlobalStudy-wide29954A=0.829C=0.170
The Genome Aggregation DatabaseOtherSub300A=0.840C=0.160
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.818C=0.181
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.880C=0.120
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs108085700.000349alcohol dependence20201924

eQTL of rs10808570 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10808570 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr8129442024129442525E069-21010
chr8129436320129436382E070-27153
chr8129436538129437183E070-26352
chr8129442024129442525E070-21010
chr8129442024129442525E071-21010
chr8129442024129442525E082-21010