rs10823825

Homo sapiens
T>C
CDH23 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0328 (9810/29868,GnomAD)
C=0281 (8202/29118,TOPMED)
C=0263 (1316/5008,1000G)
chr10:71694880 (GRCh38.p7) (10q22.1)
AD
GWASdb2
1   publication(s)
See rs on genome
183 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.71694880T>C
GRCh37.p13 chr 10NC_000010.10:g.73454637T>C
CDH23 RefSeqGeneNG_008835.1:g.302934T>C

Gene: CDH23, cadherin-related 23(plus strand)

Molecule type Change Amino acid[Codon] SO Term
CDH23 transcript variant 3NM_001171930.1:c.N/AIntron Variant
CDH23 transcript variant 4NM_001171931.1:c.N/AIntron Variant
CDH23 transcript variant 1NM_022124.5:c.N/AIntron Variant
CDH23 transcript variant 6NM_001171933.1:c.N/AGenic Upstream Transcript Variant
CDH23 transcript variant 7NM_001171934.1:c.N/AGenic Upstream Transcript Variant
CDH23 transcript variant 8NM_001171935.1:c.N/AGenic Upstream Transcript Variant
CDH23 transcript variant 9NM_001171936.1:c.N/AGenic Upstream Transcript Variant
CDH23 transcript variant 5NM_001171932.1:c.N/AGenic Downstream Transcript Variant
CDH23 transcript variant 2NM_052836.3:c.N/AGenic Downstream Transcript Variant
CDH23 transcript variant X1XM_006717940.3:c.N/AIntron Variant
CDH23 transcript variant X4XM_006717942.3:c.N/AIntron Variant
CDH23 transcript variant X2XM_011540039.2:c.N/AIntron Variant
CDH23 transcript variant X5XM_011540042.2:c.N/AIntron Variant
CDH23 transcript variant X6XM_011540043.2:c.N/AIntron Variant
CDH23 transcript variant X8XM_011540044.2:c.N/AIntron Variant
CDH23 transcript variant X9XM_011540045.2:c.N/AIntron Variant
CDH23 transcript variant X10XM_011540046.2:c.N/AIntron Variant
CDH23 transcript variant X11XM_011540047.2:c.N/AIntron Variant
CDH23 transcript variant X14XM_011540048.2:c.N/AIntron Variant
CDH23 transcript variant X15XM_011540049.2:c.N/AIntron Variant
CDH23 transcript variant X17XM_011540051.2:c.N/AIntron Variant
CDH23 transcript variant X3XM_017016499.1:c.N/AIntron Variant
CDH23 transcript variant X7XM_017016500.1:c.N/AIntron Variant
CDH23 transcript variant X13XM_017016502.1:c.N/A5 Prime UTR Variant
CDH23 transcript variant X18XM_011540052.2:c.N/AGenic Upstream Transcript Variant
CDH23 transcript variant X12XM_017016501.1:c.N/AGenic Upstream Transcript Variant
CDH23 transcript variant X19XM_017016503.1:c.N/AGenic Upstream Transcript Variant
CDH23 transcript variant X20XM_017016504.1:c.N/AGenic Upstream Transcript Variant
CDH23 transcript variant X21XM_017016505.1:c.N/AGenic Upstream Transcript Variant
CDH23 transcript variant X22XM_017016506.1:c.N/AGenic Upstream Transcript Variant
CDH23 transcript variant X23XM_017016507.1:c.N/AGenic Upstream Transcript Variant
CDH23 transcript variant X24XM_017016508.1:c.N/AGenic Upstream Transcript Variant
CDH23 transcript variant X16XR_945796.2:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.877C=0.123
1000GenomesAmericanSub694T=0.680C=0.320
1000GenomesEast AsianSub1008T=0.617C=0.383
1000GenomesEuropeSub1006T=0.623C=0.377
1000GenomesGlobalStudy-wide5008T=0.737C=0.263
1000GenomesSouth AsianSub978T=0.830C=0.170
The Genome Aggregation DatabaseAfricanSub8706T=0.846C=0.154
The Genome Aggregation DatabaseAmericanSub838T=0.620C=0.380
The Genome Aggregation DatabaseEast AsianSub1612T=0.550C=0.450
The Genome Aggregation DatabaseEuropeSub18410T=0.603C=0.396
The Genome Aggregation DatabaseGlobalStudy-wide29868T=0.671C=0.328
The Genome Aggregation DatabaseOtherSub302T=0.600C=0.400
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.718C=0.281
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs108238250.000552alcohol dependence20201924

eQTL of rs10823825 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10823825 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr107346772473468415E06713087
chr107346842173468545E06713784
chr107347190273474350E06717265
chr107347438273474446E06719745
chr107347447073474604E06719833
chr107347461073474767E06719973
chr107347482573474900E06720188
chr107347493773475012E06720300
chr107347509873475173E06720461
chr107347526573475449E06720628
chr107347545673475625E06720819
chr107344711373447265E068-7372
chr107344739073447520E068-7117
chr107344753173447578E068-7059
chr107346772473468415E06813087
chr107346842173468545E06813784
chr107347190273474350E06817265
chr107347438273474446E06819745
chr107347447073474604E06819833
chr107347461073474767E06819973
chr107347482573474900E06820188
chr107347493773475012E06820300
chr107347509873475173E06820461
chr107347526573475449E06820628
chr107347545673475625E06820819
chr107347572573475779E06821088
chr107347579373475843E06821156
chr107347603073476080E06821393
chr107347614573476473E06821508
chr107347653873476618E06821901
chr107347928773479429E06824650
chr107347950773480363E06824870
chr107348043873480523E06825801
chr107348559673488592E06830959
chr107348870073488762E06834063
chr107348884773488904E06834210
chr107348893273489428E06834295
chr107349952773499668E06844890
chr107349975873500377E06845121
chr107344317573443342E069-11295
chr107346746773467665E06912830
chr107346772473468415E06913087
chr107346842173468545E06913784
chr107347171273471886E06917075
chr107347190273474350E06917265
chr107347438273474446E06919745
chr107347447073474604E06919833
chr107347461073474767E06919973
chr107347482573474900E06920188
chr107347493773475012E06920300
chr107347509873475173E06920461
chr107347526573475449E06920628
chr107347545673475625E06920819
chr107347572573475779E06921088
chr107347579373475843E06921156
chr107347603073476080E06921393
chr107347614573476473E06921508
chr107347190273474350E07017265
chr107347438273474446E07019745
chr107347447073474604E07019833
chr107347461073474767E07019973
chr107347482573474900E07020188
chr107347493773475012E07020300
chr107347509873475173E07020461
chr107347526573475449E07020628
chr107347545673475625E07020819
chr107349975873500377E07045121
chr107344296973443029E071-11608
chr107344317573443342E071-11295
chr107345492073455079E071283
chr107345508873455156E071451
chr107345526873455534E071631
chr107345554573455606E071908
chr107345567573455725E0711038
chr107345574373455807E0711106
chr107345581573455902E0711178
chr107346772473468415E07113087
chr107346842173468545E07113784
chr107347190273474350E07117265
chr107347438273474446E07119745
chr107347447073474604E07119833
chr107347461073474767E07119973
chr107347482573474900E07120188
chr107347493773475012E07120300
chr107347509873475173E07120461
chr107347526573475449E07120628
chr107347545673475625E07120819
chr107347572573475779E07121088
chr107347579373475843E07121156
chr107347603073476080E07121393
chr107347614573476473E07121508
chr107348559673488592E07130959
chr107348870073488762E07134063
chr107349557873497359E07140941
chr107349742673497517E07142789
chr107349755673498096E07142919
chr107344317573443342E072-11295
chr107346772473468415E07213087
chr107346842173468545E07213784
chr107346863973468698E07214002
chr107346870273469012E07214065
chr107346902973469310E07214392
chr107347190273474350E07217265
chr107347438273474446E07219745
chr107347447073474604E07219833
chr107347461073474767E07219973
chr107347482573474900E07220188
chr107347493773475012E07220300
chr107347509873475173E07220461
chr107347526573475449E07220628
chr107347545673475625E07220819
chr107347572573475779E07221088
chr107347579373475843E07221156
chr107347603073476080E07221393
chr107347614573476473E07221508
chr107348559673488592E07230959
chr107348870073488762E07234063
chr107348884773488904E07234210
chr107348893273489428E07234295
chr107346737773467460E07312740
chr107346746773467665E07312830
chr107346772473468415E07313087
chr107346842173468545E07313784
chr107347190273474350E07317265
chr107347438273474446E07319745
chr107347447073474604E07319833
chr107347461073474767E07319973
chr107347482573474900E07320188
chr107347493773475012E07320300
chr107347509873475173E07320461
chr107347526573475449E07320628
chr107347545673475625E07320819
chr107347572573475779E07321088
chr107347579373475843E07321156
chr107347603073476080E07321393
chr107347887073479245E07324233
chr107347928773479429E07324650
chr107347950773480363E07324870
chr107348559673488592E07330959
chr107348870073488762E07334063
chr107348884773488904E07334210
chr107348893273489428E07334295
chr107346746773467665E07412830
chr107346772473468415E07413087
chr107346842173468545E07413784
chr107347190273474350E07417265
chr107347438273474446E07419745
chr107347447073474604E07419833
chr107347461073474767E07419973
chr107347482573474900E07420188
chr107347493773475012E07420300
chr107347509873475173E07420461
chr107347526573475449E07420628
chr107347545673475625E07420819
chr107347572573475779E07421088
chr107347579373475843E07421156
chr107347603073476080E07421393
chr107347614573476473E07421508
chr107347802673478076E07423389
chr107347813673478393E07423499
chr107348043873480523E07425801
chr107348069373480743E07426056
chr107348078373480991E07426146
chr107348536273485402E07430725
chr107348540373485584E07430766
chr107348559673488592E07430959
chr107348870073488762E07434063
chr107348884773488904E07434210
chr107348893273489428E07434295
chr107349557873497359E07440941
chr107349975873500377E07445121
chr107347190273474350E08117265
chr107349557873497359E08140941
chr107349742673497517E08142789
chr107349755673498096E08142919
chr107349815873498208E08143521
chr107342383073424009E082-30628
chr107342414473424194E082-30443
chr107342429873424348E082-30289
chr107348043873480523E08225801
chr107349557873497359E08240941
chr107349742673497517E08242789
chr107349755673498096E08242919