rs10824233

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0075 (2267/29988,GnomAD)
A=0085 (2500/29118,TOPMED)
A=0104 (521/5008,1000G)
A=0033 (127/3854,ALSPAC)
A=0032 (119/3708,TWINSUK)
chr10:74745813 (GRCh38.p7) (10q22.2)
AD
GWASdb2
1   publication(s)
See rs on genome
14 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.74745813G>A
GRCh37.p13 chr 10NC_000010.10:g.76505571G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.864A=0.136
1000GenomesAmericanSub694G=0.830A=0.170
1000GenomesEast AsianSub1008G=0.875A=0.125
1000GenomesEuropeSub1006G=0.967A=0.033
1000GenomesGlobalStudy-wide5008G=0.896A=0.104
1000GenomesSouth AsianSub978G=0.930A=0.070
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.967A=0.033
The Genome Aggregation DatabaseAfricanSub8730G=0.860A=0.140
The Genome Aggregation DatabaseAmericanSub838G=0.840A=0.160
The Genome Aggregation DatabaseEast AsianSub1620G=0.889A=0.111
The Genome Aggregation DatabaseEuropeSub18498G=0.960A=0.039
The Genome Aggregation DatabaseGlobalStudy-wide29988G=0.924A=0.075
The Genome Aggregation DatabaseOtherSub302G=0.970A=0.030
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.914A=0.085
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.968A=0.032
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs108242330.00046alcohol dependence(early age of onset)20201924
rs108242330.00093alcohol dependence20201924

eQTL of rs10824233 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10824233 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr107650887176509089E0683300
chr107650830876508375E0692737
chr107650846876508633E0692897
chr107650863976508728E0693068
chr107650873676508786E0693165
chr107650830876508375E0702737
chr107650846876508633E0702897
chr107650863976508728E0703068
chr107650873676508786E0703165
chr107650887176509089E0713300
chr107650887176509089E0723300
chr107650830876508375E0742737
chr107652457976524698E08219008
chr107652475276524859E08219181