rs10831798

Homo sapiens
T>C
MICALCL : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0425 (12734/29912,GnomAD)
C=0382 (11131/29118,TOPMED)
C=0334 (1675/5008,1000G)
C=0495 (1909/3854,ALSPAC)
C=0499 (1851/3708,TWINSUK)
chr11:12346259 (GRCh38.p7) (11p15.3)
AD
GWASdb2
1   publication(s)
See rs on genome
61 Enhancers around
17 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.12346259T>C
GRCh37.p13 chr 11NC_000011.9:g.12367806T>C

Gene: MICALCL, MICAL C-terminal like(plus strand)

Molecule type Change Amino acid[Codon] SO Term
MICALCL transcriptNM_032867.2:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.758C=0.242
1000GenomesAmericanSub694T=0.710C=0.290
1000GenomesEast AsianSub1008T=0.678C=0.322
1000GenomesEuropeSub1006T=0.520C=0.480
1000GenomesGlobalStudy-wide5008T=0.666C=0.334
1000GenomesSouth AsianSub978T=0.650C=0.350
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.505C=0.495
The Genome Aggregation DatabaseAfricanSub8704T=0.749C=0.251
The Genome Aggregation DatabaseAmericanSub834T=0.730C=0.270
The Genome Aggregation DatabaseEast AsianSub1612T=0.708C=0.292
The Genome Aggregation DatabaseEuropeSub18460T=0.473C=0.526
The Genome Aggregation DatabaseGlobalStudy-wide29912T=0.574C=0.425
The Genome Aggregation DatabaseOtherSub302T=0.560C=0.440
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.617C=0.382
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.501C=0.499
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs108317980.0000278alcoholismpha002891
rs108317980.0000278alcohol dependence20201924

eQTL of rs10831798 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10831798 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr111234650612346609E068-21197
chr111235086712351060E068-16746
chr111235147812351691E068-16115
chr111241193212412760E06844126
chr111234650612346609E069-21197
chr111235040312350457E069-17349
chr111235086712351060E069-16746
chr111235147812351691E069-16115
chr111235192312353236E069-14570
chr111234027812340415E070-27391
chr111234044512340956E070-26850
chr111234100912341274E070-26532
chr111234132612341571E070-26235
chr111235040312350457E070-17349
chr111235340212353477E070-14329
chr111235353512353593E070-14213
chr111234044512340956E071-26850
chr111234100912341274E071-26532
chr111235040312350457E071-17349
chr111235086712351060E071-16746
chr111235147812351691E071-16115
chr111241113912411882E07143333
chr111241193212412760E07144126
chr111234734112347391E072-20415
chr111235147812351691E072-16115
chr111235192312353236E072-14570
chr111241193212412760E07244126
chr111235086712351060E073-16746
chr111235147812351691E073-16115
chr111235192312353236E073-14570
chr111241113912411882E07343333
chr111241193212412760E07344126
chr111234650612346609E074-21197
chr111235040312350457E074-17349
chr111235086712351060E074-16746
chr111235147812351691E074-16115
chr111235192312353236E074-14570
chr111234027812340415E081-27391
chr111234044512340956E081-26850
chr111234100912341274E081-26532
chr111234132612341571E081-26235
chr111234196812342137E081-25669
chr111234217712342342E081-25464
chr111235192312353236E081-14570
chr111236507012365402E081-2404
chr111236673212366826E081-980
chr111238428912384364E08116483
chr111241113912411882E08143333
chr111241193212412760E08144126
chr111241277712412884E08144971
chr111241299312413053E08145187
chr111234027812340415E082-27391
chr111234044512340956E082-26850
chr111234100912341274E082-26532
chr111234132612341571E082-26235
chr111234196812342137E082-25669
chr111234217712342342E082-25464
chr111234256812342613E082-25193
chr111235147812351691E082-16115
chr111241193212412760E08244126
chr111241277712412884E08244971









Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr111239772712400096E06729921
chr111240017512400304E06732369
chr111239772712400096E06829921
chr111240017512400304E06832369
chr111239772712400096E06929921
chr111239772712400096E07029921
chr111240017512400304E07032369
chr111239772712400096E07129921
chr111240017512400304E07132369
chr111239772712400096E07229921
chr111240017512400304E07232369
chr111239772712400096E07329921
chr111240017512400304E07332369
chr111239772712400096E07429921
chr111240017512400304E08132369
chr111239772712400096E08229921
chr111240017512400304E08232369