rs10831916

Homo sapiens
C>T
TEAD1 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0260 (7786/29928,GnomAD)
T=0239 (6968/29118,TOPMED)
T=0356 (1784/5008,1000G)
T=0161 (620/3854,ALSPAC)
T=0163 (603/3708,TWINSUK)
chr11:12889689 (GRCh38.p7) (11p15.3)
AD
GWASdb2
1   publication(s)
See rs on genome
167 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.12889689C>T
GRCh37.p13 chr 11NC_000011.9:g.12911236C>T
TEAD1 RefSeqGeneNG_021302.1:g.220268C>T

Gene: TEAD1, TEA domain transcription factor 1(plus strand)

Molecule type Change Amino acid[Codon] SO Term
TEAD1 transcriptNM_021961.5:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.614T=0.386
1000GenomesAmericanSub694C=0.820T=0.180
1000GenomesEast AsianSub1008C=0.310T=0.690
1000GenomesEuropeSub1006C=0.815T=0.185
1000GenomesGlobalStudy-wide5008C=0.644T=0.356
1000GenomesSouth AsianSub978C=0.730T=0.270
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.839T=0.161
The Genome Aggregation DatabaseAfricanSub8700C=0.641T=0.359
The Genome Aggregation DatabaseAmericanSub838C=0.780T=0.220
The Genome Aggregation DatabaseEast AsianSub1618C=0.263T=0.737
The Genome Aggregation DatabaseEuropeSub18470C=0.824T=0.176
The Genome Aggregation DatabaseGlobalStudy-wide29928C=0.739T=0.260
The Genome Aggregation DatabaseOtherSub302C=0.880T=0.120
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.760T=0.239
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.837T=0.163
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs108319160.000474alcohol dependence20201924

eQTL of rs10831916 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10831916 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr111286331412864350E067-46886
chr111286449612864983E067-46253
chr111286669912868273E067-42963
chr111286831412869012E067-42224
chr111288185412882068E067-29168
chr111288211512882203E067-29033
chr111288220812882262E067-28974
chr111288746512887701E067-23535
chr111288772012888662E067-22574
chr111292380612924020E06712570
chr111286331412864350E068-46886
chr111286449612864983E068-46253
chr111286601012866499E068-44737
chr111286669912868273E068-42963
chr111286831412869012E068-42224
chr111288381712884191E068-27045
chr111290593012906029E068-5207
chr111290628412906634E068-4602
chr111291005912911256E0680
chr111292068012920868E0689444
chr111292089712920953E0689661
chr111292098712921082E0689751
chr111292134612921490E06810110
chr111292164812921702E06810412
chr111292194512922578E06810709
chr111292263812922692E06811402
chr111292273312922829E06811497
chr111292294112923199E06811705
chr111286331412864350E069-46886
chr111286449612864983E069-46253
chr111286669912868273E069-42963
chr111286831412869012E069-42224
chr111286902112869058E069-42178
chr111286909512869145E069-42091
chr111287009812870166E069-41070
chr111288381712884191E069-27045
chr111288586812886814E069-24422
chr111288746512887701E069-23535
chr111288772012888662E069-22574
chr111291005912911256E0690
chr111293517412937014E06923938
chr111286186512863303E070-47933
chr111286331412864350E070-46886
chr111286449612864983E070-46253
chr111286508812865132E070-46104
chr111286514712865197E070-46039
chr111286527112865350E070-45886
chr111286539812865474E070-45762
chr111286601012866499E070-44737
chr111286653712866593E070-44643
chr111286831412869012E070-42224
chr111286902112869058E070-42178
chr111286909512869145E070-42091
chr111286955412869614E070-41622
chr111288381712884191E070-27045
chr111288685212887061E070-24175
chr111288709512887145E070-24091
chr111288746512887701E070-23535
chr111288772012888662E070-22574
chr111289451012894565E070-16671
chr111289464112894783E070-16453
chr111289497012895049E070-16187
chr111289515412895260E070-15976
chr111293153112931759E07020295
chr111293316412933214E07021928
chr111293332612933383E07022090
chr111293355612933611E07022320
chr111293487012934941E07023634
chr111293506812935119E07023832
chr111293517412937014E07023938
chr111293786112937982E07026625
chr111293821212938319E07026976
chr111286186512863303E071-47933
chr111286449612864983E071-46253
chr111286669912868273E071-42963
chr111286831412869012E071-42224
chr111286902112869058E071-42178
chr111286909512869145E071-42091
chr111288421012885846E071-25390
chr111288685212887061E071-24175
chr111288746512887701E071-23535
chr111288772012888662E071-22574
chr111291005912911256E0710
chr111292194512922578E07110709
chr111293517412937014E07123938
chr111286331412864350E072-46886
chr111286449612864983E072-46253
chr111286669912868273E072-42963
chr111286831412869012E072-42224
chr111288421012885846E072-25390
chr111288772012888662E072-22574
chr111290576012905810E072-5426
chr111290593012906029E072-5207
chr111291005912911256E0720
chr111286186512863303E073-47933
chr111286331412864350E073-46886
chr111286449612864983E073-46253
chr111286669912868273E073-42963
chr111286831412869012E073-42224
chr111287437112874550E073-36686
chr111287460512874727E073-36509
chr111287486312876156E073-35080
chr111288381712884191E073-27045
chr111288421012885846E073-25390
chr111289060912890682E073-20554
chr111289076912890819E073-20417
chr111289093412891040E073-20196
chr111291005912911256E0730
chr111291183612911890E073600
chr111293517412937014E07323938
chr111286186512863303E074-47933
chr111286331412864350E074-46886
chr111286449612864983E074-46253
chr111286669912868273E074-42963
chr111286831412869012E074-42224
chr111287486312876156E074-35080
chr111288381712884191E074-27045
chr111288746512887701E074-23535
chr111288772012888662E074-22574
chr111288874912888799E074-22437
chr111288889112889296E074-21940
chr111288930912889419E074-21817
chr111288949312889543E074-21693
chr111288954512889773E074-21463
chr111291005912911256E0740
chr111293517412937014E07423938
chr111286331412864350E081-46886
chr111286449612864983E081-46253
chr111286601012866499E081-44737
chr111286653712866593E081-44643
chr111286669912868273E081-42963
chr111286831412869012E081-42224
chr111286902112869058E081-42178
chr111286909512869145E081-42091
chr111288381712884191E081-27045
chr111288421012885846E081-25390
chr111288685212887061E081-24175
chr111288709512887145E081-24091
chr111288746512887701E081-23535
chr111293355612933611E08122320
chr111293366612933819E08122430
chr111293405612934110E08122820
chr111293425312934303E08123017
chr111293438912934491E08123153
chr111293452012934570E08123284
chr111293487012934941E08123634
chr111293506812935119E08123832
chr111293517412937014E08123938
chr111293786112937982E08126625
chr111286449612864983E082-46253
chr111286508812865132E082-46104
chr111286514712865197E082-46039
chr111286527112865350E082-45886
chr111286539812865474E082-45762
chr111286601012866499E082-44737
chr111286653712866593E082-44643
chr111286669912868273E082-42963
chr111286831412869012E082-42224
chr111286902112869058E082-42178
chr111286909512869145E082-42091
chr111288381712884191E082-27045
chr111288685212887061E082-24175
chr111288709512887145E082-24091
chr111288746512887701E082-23535
chr111288772012888662E082-22574
chr111289802312898105E082-13131
chr111293517412937014E08223938